| 1191927-94-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• CAS: 1191927-94-2
• 化学式: C₁₈H₂₂O₇
• 分子量: 350.368
• InChiKey: XCMMWNQSEPKQDV-WFGGFHQOSA-N

反应信息

• 作为反应物：
  描述：

  在 甲烷磺酸 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 3.0h， 以80%的产率得到
  参考文献：
  名称：

  Synthesis of 9-oxa-noradamantane derivative, an aesthetically pleasing ‘oxa-basket’

  摘要：

  A simple protocol for the synthesis of an aesthetically pleasing 'oxa-basket' (5-methoxy-2,8,13-trioxapentacyclo[7.2.1.1.(5,12)0.(4,11)0(6,10)]tridecane-3,7-dione), possessing 9-oxa-noradamantane core, is described. The readily available diquinane based dichloro bis-gamma-lactone precursor upon treatment with MeSO3H furnished dichloro 'oxa-basket' which was dechlorinated using TBTH/AIBN to obtain the title compound. The key role of the chlorines was demonstrated by replacement with hydrogen or allyl substituents which redirects the cascade to simple hydrolysis products. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.143
• 作为产物：
  描述：

  、 烯丙基三丁基锡 在 偶氮二异丁腈 作用下， 以 苯 为溶剂， 反应 4.0h， 以84%的产率得到
  参考文献：
  名称：

  Synthesis of 9-oxa-noradamantane derivative, an aesthetically pleasing ‘oxa-basket’

  摘要：

  A simple protocol for the synthesis of an aesthetically pleasing 'oxa-basket' (5-methoxy-2,8,13-trioxapentacyclo[7.2.1.1.(5,12)0.(4,11)0(6,10)]tridecane-3,7-dione), possessing 9-oxa-noradamantane core, is described. The readily available diquinane based dichloro bis-gamma-lactone precursor upon treatment with MeSO3H furnished dichloro 'oxa-basket' which was dechlorinated using TBTH/AIBN to obtain the title compound. The key role of the chlorines was demonstrated by replacement with hydrogen or allyl substituents which redirects the cascade to simple hydrolysis products. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.07.143