(4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-[2-((1aS,3S,4S,4aS,5S,7R,8aR)-5-hydroxy-3,7-dimethyl-octahydro-1-oxa-cyclopropa[d]naphthalen-4-yl)-ethyl]-tetrahydro-pyran-2-one | 118682-48-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: (4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-[2-((1aS,3S,4S,4aS,5S,7R,8aR)-5-hydroxy-3,7-dimethyl-octahydro-1-oxa-cyclopropa[d]naphthalen-4-yl)-ethyl]-tetrahydro-pyran-2-one
• CAS: 118682-48-7
• 化学式: C₂₅H₄₄O₅Si
• 分子量: 452.707
• InChiKey: FZKIEKVZUXEZKH-QXLDQVLQSA-N

反应信息

• 作为产物：
  描述：

  (4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-[2-((1S,2S,6S,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,3,5,6,7,8,8a-octahydro-naphthalen-1-yl)-ethyl]-tetrahydro-pyran-2-one 在 bis(acetylacetonate)oxovanadium 叔丁基过氧化氢 作用下， 以81%的产率得到(4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-[2-((1aS,3S,4S,4aS,5S,7R,8aR)-5-hydroxy-3,7-dimethyl-octahydro-1-oxa-cyclopropa[d]naphthalen-4-yl)-ethyl]-tetrahydro-pyran-2-one
  参考文献：
  名称：

  Remote diastereoselection in the asymmetric total synthesis of mevinolin

  摘要：

  DOI：

  10.1021/ja00189a037