(E)-6-(3,4-dimethoxyphenyl)-3-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-N,N-diethyl-3-methyl-4-oxohex-5-enamide | 1462868-88-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: (E)-6-(3,4-dimethoxyphenyl)-3-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-N,N-diethyl-3-methyl-4-oxohex-5-enamide
• CAS: 1462868-88-7
• 化学式: C₃₀H₃₇NO₇
• 分子量: 523.6
• InChiKey: UWVCYNXVZRDWSD-UNZYHPAISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  38
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  91.4
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• Uses of curcumin derivative
  申请人：Merry Life Biomedical Company, Ltd.

  公开号：US11135185B2

  公开（公告）日：2021-10-05

  The invention provides a method for preventing and/or treating Alzheimer's disease in a subject in need of such treatment, comprising administrating to said subject an effective amount of a curcumin derivative, TML-6, and optionally a pharmaceutically acceptable carrier or excipient.

  本发明提供了一种预防和/或治疗需要阿尔茨海默病的受试者的方法，包括向所述受试者施用有效量的姜黄素衍生物 TML-6，以及可选的药学上可接受的载体或赋形剂。
• Uses of Curcumin Derivative
  申请人：Merry Life Biomedical Company, Ltd.

  公开号：US20190290604A1

  公开（公告）日：2019-09-26

  The invention provides a method for preventing and/or treating Alzheimer's disease in a subject in need of such treatment, comprising administrating to said subject an effective amount of a curcumin derivative, TML-6, and optionally a pharmaceutically acceptable carrier or excipient.