Acetic acid 3-oxo-3-((1R,2S,3R,4R,4aS,6S,8aS)-2,3,4-trihydroxy-1,2,6-trimethyl-decahydro-naphthalen-1-yl)-propyl ester | 678193-69-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Acetic acid 3-oxo-3-((1R,2S,3R,4R,4aS,6S,8aS)-2,3,4-trihydroxy-1,2,6-trimethyl-decahydro-naphthalen-1-yl)-propyl ester
• CAS: 678193-69-6
• 化学式: C₁₈H₃₀O₆
• 分子量: 342.433
• InChiKey: SYWOYKTUWCPMDX-HEAJQOATSA-N

反应信息

• 作为反应物：
  描述：

  4-溴苯甲酰氯 、 Acetic acid 3-oxo-3-((1R,2S,3R,4R,4aS,6S,8aS)-2,3,4-trihydroxy-1,2,6-trimethyl-decahydro-naphthalen-1-yl)-propyl ester 在 吡啶 、 N,N-二甲基吡啶-1-胺 作用下， 以8.4 mg的产率得到4-Bromo-benzoic acid (1R,2R,3S,4R,4aS,7S,8aS)-4-(3-acetoxy-propionyl)-2,3-dihydroxy-3,4,7-trimethyl-decahydro-naphthalen-1-yl ester
  参考文献：
  名称：

  Aspermytin A: a new neurotrophic polyketide isolated from a marine-derived fungus of the genus Aspergillus

  摘要：

  A new polyketide, aspermytin A (1), was isolated from a cultured marine fungus, Aspergillus sp., which was separated from the mussel, Mytilus edulis. Its structure was elucidated on the basis of their spectral data, and the absolute configuration of I was determined by the CD spectrum. Aspermytin A induced neurite outgrowth in rat pheochromocytoma (PC-12) cells at concentration of 50muM. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2003.10.053
• 作为产物：
  描述：

  aspermytin A acetate 在 四氧化锇 、 N-甲基吗啉氧化物 作用下， 以 叔丁醇 为溶剂， 反应 120.0h， 以7.9 mg的产率得到Acetic acid 3-oxo-3-((1R,2S,3R,4R,4aS,6S,8aS)-2,3,4-trihydroxy-1,2,6-trimethyl-decahydro-naphthalen-1-yl)-propyl ester
  参考文献：
  名称：

  Aspermytin A: a new neurotrophic polyketide isolated from a marine-derived fungus of the genus Aspergillus

  摘要：

  A new polyketide, aspermytin A (1), was isolated from a cultured marine fungus, Aspergillus sp., which was separated from the mussel, Mytilus edulis. Its structure was elucidated on the basis of their spectral data, and the absolute configuration of I was determined by the CD spectrum. Aspermytin A induced neurite outgrowth in rat pheochromocytoma (PC-12) cells at concentration of 50muM. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2003.10.053