1-phenylnon-8-ene-1,5-dione | 1195847-92-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-phenylnon-8-ene-1,5-dione
• CAS: 1195847-92-7
• 化学式: C₁₅H₁₈O₂
• 分子量: 230.307
• InChiKey: OSAJCEGSBHOXRC-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  (E)-1-(2-benzylidenecyclopropyl)pent-4-en-1-one 在 水 、 palladium(II) bromide 作用下， 以 四氢呋喃 为溶剂， 反应 3.0h， 以62%的产率得到1-phenylnon-8-ene-1,5-dione
  参考文献：
  名称：

  Pd(0) or Pd(II)-catalyzed ring-opening reactions of benzylidene- and alkylidenecyclopropyl ketones and aldehydes

  摘要：

  Pd(0) catalyzed reactions of methylenecyclopropyl carbonyl compounds afforded a convenient method for the synthesis of conjugate (E,E)-1,3-diene derivatives 2 in good to excellent yields. Moreover, we also found that Pd(II)-catalyzed reactions of methylenecyclopropyl carbonyl compounds with water gave 1,5-diketones in good to high yields via a carbene-palladium intermediate. The plausible reaction mechanisms have also been provided on the basis of control and O-18-labeling experiments. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.08.044