1-cyclopropyl-6-fluoro-4-oxo-7-[(tetrahydro-2-furanylmethyl)amino]-1,4-dihydro-3-quinolinecarboxylic acid | 341004-99-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-cyclopropyl-6-fluoro-4-oxo-7-[(tetrahydro-2-furanylmethyl)amino]-1,4-dihydro-3-quinolinecarboxylic acid
• 英文别名: 1-Cyclopropyl-6-fluoro-4-oxo-7-(oxolan-2-ylmethylamino)quinoline-3-carboxylic acid
• CAS: 341004-99-7
• 化学式: C₁₈H₁₉FN₂O₄
• 分子量: 346.358
• InChiKey: INXZDLFCXCYGHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  78.9
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES
  申请人：New Pharma Research Sweden AB

  公开号：EP1230235A1

  公开（公告）日：2002-08-14
• US6967205B1
  申请人：——

  公开号：US6967205B1

  公开（公告）日：2005-11-22
• [EN] COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES<br/>[FR] COMPOSES ANTIBACTERIENS ET ANTIPARASITAIRES
  申请人：NEW PHARMA RES SWEDEN AB

  公开号：WO2001036408A1

  公开（公告）日：2001-05-25

  There are provided novel compounds which have both antibacterial and antiparasitic properties, thereby reducing the need for using several compounds in combined antibacterial and antiparasitic treatment of livestock. The present novel compounds are especially well suited for treatment of coccidiosis, and they are represented by general formula (I) wherein R1-R6, X and A are as defined in the specification.