2'.3'-O-isopropylidene-6-N-(4-nitrobenzyl)adenosine | 63554-95-0

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷
• 英文名称: 2'.3'-O-isopropylidene-6-N-(4-nitrobenzyl)adenosine
• 英文别名: 2'-3'-O-Isopropyliden-N6-p-nitrobenuyladenosin；O^2'_,O3'-isopropylidene-N⁶-(4-nitro-benzyl)-adenosine
• CAS: 63554-95-0
• 化学式: C₂₀H₂₂N₆O₆
• 分子量: 442.431
• InChiKey: CTMHFBDKTRELJU-NVQRDWNXSA-N

物化性质

• 沸点：
  700.7±70.0 °C(Predicted)
• 密度：
  1.65±0.1 g/cm3(Predicted)

反应信息

• 作为产物：
  描述：

  2',3'-异丙叉腺苷 、 对硝基溴化苄 在 二甲胺 作用下， 生成 2'.3'-O-isopropylidene-6-N-(4-nitrobenzyl)adenosine
  参考文献：
  名称：

  Synthesis of Substituted-Benzyl and Sugar-Modified Analogues of 6-N-(4-Nitrobenzyl)adenosine and Their Interactions with “ES” Nucleoside Transport Systems

  摘要：

  Four classes of 6-X-benzylated purine nucleosides, (i) 6-N-(substituted-benzyl)adenosines, (ii) 6-N-(4-nitrobenzyl)adenine nucleosides with modified sugars, (iii) 6-N(S)-(4-azidobenzy1) derivatives of adenosine, 6-thioinosine, and 6-thioguanosine, and (iv) 6-N-{4-N-[acyl(sulfonyl)amino]benzyl} adenosines, were synthesized and their binding interactions with ''es-NT'' (equilibrative, inhibitor-sensitive nucleoside transport) systems were studied. Several tight-binding analogues were found.

  DOI：

  10.1080/15257779408012177