3-({[1-(4-fluorophenyl)ethyl](quinolin-3-ylcarbonyl)amino}methyl)benzoic acid | 1398582-79-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3-({[1-(4-fluorophenyl)ethyl](quinolin-3-ylcarbonyl)amino}methyl)benzoic acid
• 英文别名: 3-({N-[1-(4-fluorophenyl)ethyl]-1-quinolin-3-ylformamido}methyl)benzoic acid；3-[[1-(4-fluorophenyl)ethyl-(quinoline-3-carbonyl)amino]methyl]benzoic acid
• CAS: 1398582-79-0
• 化学式: C₂₆H₂₁FN₂O₃
• 分子量: 428.463
• InChiKey: BXNMZRPTQFVRFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  32
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  70.5
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• METHODS FOR DETECTING DISORDERS RELATED TO CALCIUM DISCHARGE FROM INTRACELLULAR STORES
  申请人：The Regents of the University of California

  公开号：US20210311075A1

  公开（公告）日：2021-10-07

  Provided herein are methods for determining whether a subject has an increased likelihood of having a disorder related to abnormal intracellular calcium store discharge. In some embodiments, the method is useful for determining whether the subject has an increased likelihood of having a neurodegenerative disease, skeletal muscle disease, cardiac muscle disease, autoimmune disease, cancer, diabetes, or has been exposed to an environmental pollutant. Kits are also provided herein.