cis-10-(4-methoxy-benzoyl)-9.10-dihydro-anthracene-carboxylic acid-(9)-methyl ester | 102663-84-3

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: cis-10-(4-methoxy-benzoyl)-9.10-dihydro-anthracene-carboxylic acid-(9)-methyl ester
• 英文别名: cis-10-(4-methoxy-benzoyl)-9.10-dihydro-anthracene-carboxylic acid-(9)-methyl ester；cis-10-(4-Methoxy-benzoyl)-9.10-dihydro-anthracen-carbonsaeure-(9)-methylester
• CAS: 102663-84-3
• 化学式: C₂₄H₂₀O₄
• 分子量: 372.42
• InChiKey: QPWKZUZFHTZIRD-SZPZYZBQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.33
• 重原子数：
  28.0
• 可旋转键数：
  4.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  cis-10-(4-methoxy-benzoyl)-9.10-dihydro-anthracene-carboxylic acid-(9)-methyl ester 在 盐酸 作用下， 生成 cis-10-(4-methoxy-benzoyl)-9,10-dihydro-anthracene-9-carboxylic acid
  参考文献：
  名称：

  RIGAUDY, Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1949, vol. 229, # 19, p. 938 - 940

  摘要：

  DOI：
• 作为产物：
  描述：

  cis-9-chlorocarbonyl-9,10-dihydro-anthracene-carboxylic acid-(10)-methyl ester 、 苯甲醚 在 三氯化铝 作用下， 生成 cis-10-(4-methoxy-benzoyl)-9.10-dihydro-anthracene-carboxylic acid-(9)-methyl ester
  参考文献：
  名称：

  Effects of blockers of carbohydrate and lipid metabolism on expression of mRNA of some hypothalamic neuropeptides

  摘要：

  The effects of single injections of 2-deoxyglucose or 2-mercaptoacetate on the expression of mRNA of neuropeptide Y, pro-opiomelanocortin, and melanin-concentrating hormone in rat hypothalamus were studied by in situ hybridization in order to elucidate the role of these neuropeptides in the mechanisms of alimentary behavior caused by decreased levels of available fatty acids and glucose. The levels of neuropeptide Y mRNA in arcuate nuclei neurons are significantly increased under conditions of glucose deficiency, while the synthesis of melanin-concentrating hormone in the lateral hypothalamic neurons is increased in fatty acid deficiency. These data indicate that glyco- and lipodeprivation are different metabolic signals activating various neuropeptide systems responsible for alimentary behavior.

  DOI：

  10.1007/bf02766089