2-(5-Aminopentyl)-chinolin | 59082-53-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 2-(5-Aminopentyl)-chinolin
• 英文别名: 5-Quinolin-2-ylpentan-1-amine
• CAS: 59082-53-0
• 化学式: C₁₄H₁₈N₂
• 分子量: 214.31
• InChiKey: VCVURNRHCSLZTP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  38.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Substituted 2,4 diamino-quinoline as new anticancer agents
  申请人：GENOSCIENCE PHARMA

  公开号：US10722505B2

  公开（公告）日：2020-07-28

  The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives, their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention are useful for the treatment and prevention of proliferative neoplastic and non-neoplastic diseases.

  本发明涉及新型 2-伯氨基-4-仲氨基喹啉衍生物、其制造方法、包含它们的药物组合物及其作为药物的用途。本发明的活性化合物可用于治疗和预防增殖性肿瘤性和非肿瘤性疾病。
• SUBSTITUTED 2,4 DIAMINO-QUINOLINE AS NEW ANTICANCER AGENTS
  申请人：Genoscience Pharma SAS

  公开号：EP3212629B1

  公开（公告）日：2018-10-24
• [EN] SUBSTITUTED 2,4 DIAMINO-QUINOLINE AS NEW ANTICANCER AGENTS<br/>[FR] 2,4-DIAMINO-QUINOLÉINE SUBSTITUÉE SERVANT DE NOUVEAUX AGENTS ANTICANCÉREUX
  申请人：GENOSCIENCE PHARMA

  公开号：WO2016067112A1

  公开（公告）日：2016-05-06

  The present invention relates to novel 2-primary amino-4-secondary amino-quinoline derivatives, their manufacture, pharmaceutical compositions comprising them and their use as medicaments. The active compounds of the present invention are useful for the treatment and prevention of proliferative neoplastic and non-neoplastic diseases.