ethyl 2,5-dimethoxy-4-methylcinnamate | 81129-33-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: ethyl 2,5-dimethoxy-4-methylcinnamate
• CAS: 81129-33-1
• 化学式: C₁₄H₁₈O₄
• 分子量: 250.295
• InChiKey: VALHSIBANMWHEK-UHFFFAOYSA-N

物化性质

• 沸点：
  373.0±37.0 °C(Predicted)
• 密度：
  1.082±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

反应信息

• 作为反应物：
  描述：

  ethyl 2,5-dimethoxy-4-methylcinnamate 、 dimethylaminoethyl-p-tolyloxosulfonium fluoroborate 在 sodium hydride 作用下， 生成 ethyl 2-(2,5-dimethoxy-4-methylphenyl)-3-methylcyclopropanecarboxylate
  参考文献：
  名称：

  Isomeric cyclopropyl ring-methylated homologs of trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine, an hallucinogen analog

  摘要：

  The hallucinogen analogue trans-2-(2,5-dimethoxy-4-methylphenyl)cyclopropylamine was modified by adding a 3-methyl group, either cis or trans with respect to the amino group. These two isomeric cyclopropyl ring-methylated compounds were then tested for activity in the mouse ear-scratch assay and for a contractile effect in the rat fundus preparation. Neither compound was found to possess appreciable activity when compared to the nonmethylated parent, in either assay.

  DOI：

  10.1021/jm00347a009