4,4'-(1-Phenylprop-1-ene-3,3-diyl)bis(N,N-dimethylaniline) | 83994-88-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: 4,4'-(1-Phenylprop-1-ene-3,3-diyl)bis(N,N-dimethylaniline)
• 英文别名: 4-[1-[4-(dimethylamino)phenyl]-3-phenylprop-2-enyl]-N,N-dimethylaniline
• CAS: 83994-88-1
• 化学式: C₂₅H₂₈N₂
• 分子量: 356.511
• InChiKey: GHWNVTBLEHEHHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N,N-二甲基苯胺 、 肉桂醛 在 sodium iodine dichloride 作用下， 以 水 、 乙腈 为溶剂， 反应 5.0h， 以55%的产率得到4,4'-(1-Phenylprop-1-ene-3,3-diyl)bis(N,N-dimethylaniline)
  参考文献：
  名称：

  Efficient Synthesis of Bis(4-Dimethaminophenyl)arylmethanes and Bis(4-Diamethaminophenyl)alkanes Using Iodine Reagent

  摘要：

  A novel synthetic utility of NaICl2 for the preparation of bis(4-dimethaminophenyl)arylmethanes and bis(4-dimethaminophenyl)alkanes is described. In the presence of an aqueous solution of NaICl2, the reaction of arenes with aromatic aldehydes gives corresponding triarylmethane derivatives regioselectively in moderate to good yields. The method is also useful for the preparation of diarylalkane derivatives by using aliphatic aldehydes. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications((R)) to view the free supplemental file.

  DOI：

  10.1080/00397911.2012.680569

文献信息

• Efficient Synthesis of Bis(4-Dimethaminophenyl)arylmethanes and Bis(4-Diamethaminophenyl)alkanes Using Iodine Reagent
  作者：Harshal M. Bachhav、Balaram S. Takale、Vikas N. Telvekar

  DOI：10.1080/00397911.2012.680569

  日期：2013.7.18

  A novel synthetic utility of NaICl2 for the preparation of bis(4-dimethaminophenyl)arylmethanes and bis(4-dimethaminophenyl)alkanes is described. In the presence of an aqueous solution of NaICl2, the reaction of arenes with aromatic aldehydes gives corresponding triarylmethane derivatives regioselectively in moderate to good yields. The method is also useful for the preparation of diarylalkane derivatives by using aliphatic aldehydes. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications((R)) to view the free supplemental file.