2,2,2-Trifluoro-1-(5-tetradecyloxy-furan-2-yl)-ethanone | 62473-24-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,2,2-Trifluoro-1-(5-tetradecyloxy-furan-2-yl)-ethanone
• 英文别名: 2,2,2-Trifluoro-1-(5-tetradecoxyfuran-2-yl)ethanone
• CAS: 62473-24-9
• 化学式: C₂₀H₃₁F₃O₃
• 分子量: 376.46
• InChiKey: KFVJTCGNINUUGJ-UHFFFAOYSA-N

物化性质

• 熔点：
  55-57 °C(Solv: hexane (110-54-3))
• 沸点：
  408.4±40.0 °C(Predicted)
• 密度：
  1.049±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  26
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  39.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  2-tetradecyloxy-furan 、 三氟乙酸酐 以82%的产率得到
  参考文献：
  名称：

  PARKER R. A.; KARIYA T.; GRISAR J. M.; PETROW V., J. MED. CHEM. , 1977, 20, NO 6, 781-791

  摘要：

  DOI：

文献信息

• ANTI-VIRAL COMBINATION THERAPY
  申请人：KOYUNCU Emre

  公开号：US20150139949A1

  公开（公告）日：2015-05-21

  The present invention provides methods and compounds for treating viral infections using combinations modulators of an HCV-associated component and modulators of host cell enzymes. The present invention also provides methods and compounds for treating viral infections using combinations of modulators of host cell enzymes and other agents that work, at least in part by modulating hos factors.
• [EN] ANTI-VIRAL COMBINATION THERAPY<br/>[FR] POLYTHÉRAPIE ANTIVIRALE
  申请人：UNIV PRINCETON

  公开号：WO2012139028A2

  公开（公告）日：2012-10-11

  The present invention provides methods and compounds for treating viral infections using combinations modulators of an HCV-associated component and modulators of host cell enzymes. The present invention also provides methods and compounds for treating viral infections using combinations of modulators of host cell enzymes and other agents that work, at least in part by modulating host factors.