Sorbitol ethylene oxide | 31307-92-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Sorbitol ethylene oxide
• 英文别名: (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol;oxirane
• CAS: 31307-92-3
• 化学式: C8H18O7
• 分子量: 226.22
• InChiKey: RYOCYIVCDUMYAL-VFQQELCFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.57
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  134
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  山梨醇 、 sodium hydroxide 在 氮 、 水 、 环氧乙烷 作用下， 反应 3.0h， 以The reaction provided a sorbitol ethylene oxide 29.9 mol adduct (hereinafter,的产率得到Sorbitol ethylene oxide
  参考文献：
  名称：

  Multi-branched polyalkylene glycol polymer, method for producing the same, and admixture for cement

  摘要：

  本发明提供了一种多支链聚烯醇醚聚合物，可用于各种应用，特别是用作水泥外加剂、分散剂、水泥外加剂和包含它们的水泥组合物，以及具有聚烯醇醚链的硫醇化合物，可用于聚合物等材料，以及一种低成本、易于有效生产多支链聚烯醇醚聚合物和具有聚烯醇醚链的硫醇化合物的方法。多支链聚合物包括：聚烯醇醚链；具有三个或更多活性氢原子的化合物残留物；以及具有从乙烯单体组分衍生的构成单元的聚合物部分，聚烯醇醚链的一端与残留物结合，聚烯醇醚链的另一端的至少一个末端氧原子通过有机残基直接或通过有机残基与聚合物部分的主链末端结合。

  公开号：

  US08476341B2

文献信息

• Shape-retentive hydrogel particle aggregates and their uses
  申请人：——

  公开号：US20040086548A1

  公开（公告）日：2004-05-06

  The present invention is related to hydrogel particles and aggregates formed therefrom having characteristics including, without limitation, shape-retentiveness, elasticity, controllable pore sizes and controllable degradation rates that render them useful for a wide variety of applications including, without limitation, the controlled release of biologically active substances, in vivo medical devices, tissue growth scaffolding and tissue replacement.

  本发明涉及具有以下特征的水凝胶颗粒和聚集体，包括但不限于保持形状、具有弹性、可控的孔径大小和可控的降解速率，使它们适用于广泛的应用，包括但不限于生物活性物质的控制释放、体内医疗器械、组织生长支架和组织替代。
• SHAPE-RETENTIVE HYDROGEL PARTICLE AGGREGATES AND THEIR USES
  申请人：St. John John V.

  公开号：US20080166409A1

  公开（公告）日：2008-07-10

  The present invention is related to hydrogel particles and aggregates formed therefrom having characteristics including, without limitation, shape-retentiveness, elasticity, controllable pore sizes and controllable degradation rates that render them useful for a wide variety of applications including, without limitation, the controlled release of biologically active substances, in vivo medical devices, tissue growth scaffolding and tissue replacement.

  本发明涉及水凝胶颗粒及由其形成的聚集体，其特征包括但不限于形状保持性、弹性、可控孔径和可控降解速率，使它们在各种应用中有用，包括但不限于生物活性物质的控制释放、体内医疗器械、组织生长支架和组织替代。
• MULTI-BRANCHED POLYALKYLENE GLYCOL POLYMER, METHOD FOR PRODUCING THE SAME, AND ADMIXTURE FOR CEMENT
  申请人：Sakamoto Noboru

  公开号：US20110160393A1

  公开（公告）日：2011-06-30

  The present invention provides a multi-branched polyalkylene glycol polymer useful for various applications, especially for an admixture for cement, a dispersant, admixture for cement, and cement composition each comprising the same, a thiol compound having a polyalkylene glycol chain useful for materials and the like of the polymer, and a method for easily and effectively producing the multi-branched polyalkylene glycol polymer and the thiol compound having a polyalkylene glycol chain at low cost. The multi-branched polymer comprises: a polyalkylene glycol chain; a residue of a compound having three or more active hydrogen atoms; and a polymer portion having a constitutional unit derived from a vinyl monomer component, one end of the polyalkylene glycol chain bonding to the residue, and a terminal oxygen atom of at least one of the other ends of the polyalkylene glycol chain bonding to a main chain end of the polymer portion directly or via an organic residue.

  本发明提供了一种多支链聚烷基醚聚合物，适用于各种应用，特别是水泥掺合剂、分散剂、水泥掺合剂和包含它们的水泥组合物，以及具有聚烷基醚链的巯基化合物，用于聚合物等材料，以及一种低成本、易于有效生产多支链聚烷基醚聚合物和具有聚烷基醚链的巯基化合物的方法。多支链聚合物包括：聚烷基醚链；具有三个或更多活性氢原子的化合物残基；以及具有从乙烯单体组分衍生的构成单元的聚合物部分，聚烷基醚链的一端与残基结合，聚烷基醚链的至少一个其他端的端氧原子直接或通过有机残基与聚合物部分的主链端结合。
• HYDROGEL WOUND DRESSING AND BIOMATERIALS FORMED IN SITU AND THEIR USES
  申请人：St. John John

  公开号：US20110123621A1

  公开（公告）日：2011-05-26

  The present invention relates to a method of forming shape-retentive and shape-conforming aggregate wound dressings and biomaterials composed of gel nanoparticles and wound or bodily fluid in which the aggregates are held together by non-covalent bond physical forces such as, without limitation, hydrophobic-hydrophilic interactions and hydrogen bonds. The method comprises introducing a dry powder of gel nanoparticles to a wound site in which the nanoparticles absorb some of the blood or wound exudate and coalesce in situ into the claimed shape-retentive aggregate dressing. The method also comprises introducing the dry nanoparticle powder in or on a wet bodily tissue in vivo to form the claimed shape-retentive biomaterial. In addition, the method also comprises incorporating biomedical agents to produce medicated aggregate dressings or biomaterials for a variety of medical applications. This invention also relates to uses of the method of formation of the shape-retentive aggregates of gel nanoparticles.

  本发明涉及一种形成保持形状和适应形状的聚集伤口敷料和生物材料的方法，其由凝胶纳米粒子和伤口或体液组成，这些聚集体由非共价键物理力保持在一起，例如，但不限于疏水-亲水相互作用和氢键。该方法包括将凝胶纳米粒子的干粉引入伤口部位，其中纳米粒子吸收一些血液或伤口渗出物，并在现场凝聚成所述的保持形状的聚集敷料。该方法还包括将干纳米粒子粉末引入或涂覆于体内湿润的组织中，以形成所述的保持形状的生物材料。此外，该方法还包括将生物医学剂合并进来，以生产用于各种医疗应用的医用聚集敷料或生物材料。本发明还涉及使用凝胶纳米粒子形成保持形状的聚集体的方法。
• Hydrogel wound dressing and biomaterials formed in situ and their uses
  申请人：John John ST.

  公开号：US20090196936A1

  公开（公告）日：2009-08-06

  The present invention relates to a method of forming shape-retentive and shape-conforming aggregate wound dressings and biomaterials composed of gel nanoparticles and wound or bodily fluid in which the aggregates are held together by non-covalent bond physical forces such as, without limitation, hydrophobic-hydrophilic interactions and hydrogen bonds. The method comprises introducing a dry powder of gel nanoparticles to a wound site in which the nanoparticles absorb some of the blood or wound exudate and coalesce in situ into the claimed shape-retentive aggregate dressing. The method also comprises introducing the dry nanoparticle powder in or on a wet bodily tissue in vivo to form the claimed shape-retentive biomaterial. In addition, the method also comprises incorporating biomedical agents to produce medicated aggregate dressings or biomaterials for a variety of medical applications. This invention also relates to uses of the method of formation of the shape-retentive aggregates of gel nanoparticles.

  本发明涉及一种形成保持形状和适应形状的集合伤口敷料和生物材料的方法，该生物材料由凝胶纳米颗粒和伤口或体液组成，其中集合体由非共价键物理力保持在一起，例如，疏水-亲水相互作用和氢键等。该方法包括将凝胶纳米颗粒的干粉引入伤口部位，在其中纳米颗粒吸收部分血液或伤口渗出物，并在原地凝聚成所述保持形状的集合敷料。该方法还包括将干纳米颗粒粉末引入或涂在体内的湿润组织上，以形成所述保持形状的生物材料。此外，该方法还包括将生物医学药剂并入其中，以生产用于各种医疗应用的医疗集合敷料或生物材料。本发明还涉及利用凝胶纳米颗粒形成保持形状的集合体的方法。