epichlorohydrin | 6798-40-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: epichlorohydrin
• 英文别名: 2-Ethoxy-3-chlorpropanol；3-chloro-2-ethoxy-propan-1-ol；3-Chloro-2-ethoxypropan-1-ol
• CAS: 6798-40-9
• 化学式: C₅H₁₁ClO₂
• mdl: MFCD19234633
• 分子量: 138.594
• InChiKey: XBVIXNODTHEOFC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-Aethoxyoxetan 在 盐酸 作用下， 生成 epichlorohydrin
  参考文献：
  名称：

  Synthesis of 3-alkoxyoxetanes

  摘要：

  DOI：

  10.1021/jo00815a007

文献信息

• Investigation of the catalytic activity of an electron-deficient vanadium(IV) tetraphenylporphyrin: A new, highly efficient and reusable catalyst for ring-opening of epoxides
  作者：S. Abdolmanaf Taghavi、Majid Moghadam、Iraj Mohammadpoor-Baltork、Shahram Tangestaninejad、Valiollah Mirkhani、Ahmad Reza Khosropour、Venus Ahmadi

  DOI：10.1016/j.poly.2011.06.008

  日期：2011.8

  In this work, the catalytic activity of high-valent tetraphenylporphyrinatovanadium(IV) trifluoromethanesulfonate, [V-IV(TPP)(OTf)(2)], in the nucleophilic ring-opening of epoxides is reported. This new V(IV) catalyst was used as an efficient catalyst for alcoholysis with primary (methanol, ethanol and n-propanol), secondary (iso-propanol) and tertiary alcohols (tert-butanol), hydrolysis and acetolysis of epoxides with acetic acid and also for the conversion of epoxides to 1,2-diacetates with acetic anhydride, conversion of epoxides to thiiranes with ammonium thiocyanate and thiourea, and for conversion of epoxides to acetonides with acetone. The catalyst was reused several times without loss of its activity. (C) 2011 Elsevier Ltd. All rights reserved.
• Enhanced metal loading in SBA-15-type catalysts facilitated by salt addition: Synthesis, characterization and catalytic epoxide alcoholysis activity of molybdenum incorporated porous silica
  作者：Sridhar Budhi、Chorthip Peeraphatdit、Svitlana Pylypenko、Vy H.T. Nguyen、Emily A. Smith、Brian G. Trewyn

  DOI：10.1016/j.apcata.2014.01.055

  日期：2014.4

  We report a novel method to increase the metal loading in SBA-15 silica matrix via direct synthesis. It was demonstrated through the synthesis and characterization of a series of molybdenum containing SBA-15 mesoporous silica catalysts prepared with and without diammonium hydrogen phosphate (DHP) as an additive. Catalysts prepared with DHP show a 2-3 times increase in incorporation of molybdenum in the silica matrix and pore size enlargement. The synthesized catalysts were characterized using nitrogen sorption, X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and inductively coupled plasma-optical emission spectroscopy (ICP-OES). The catalytic activity of catalysts prepared with DHP for alcoholysis of epoxides was superior than the catalyst prepared without DHP. Alcoholysis of epoxides was demonstrated for a range of alcohols and epoxides under ambient conditions in as little as 30 min with high selectivity. (C) 2014 Elsevier B.V. All rights reserved.