3,3-diphenyl-5-(4-(trifluoromethyl)phenyl)-1,2,4-trioxolane | 131178-86-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,3-diphenyl-5-(4-(trifluoromethyl)phenyl)-1,2,4-trioxolane
• 英文别名: 3,3-diphenyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-trioxolane
• CAS: 131178-86-4
• 化学式: C₂₁H₁₅F₃O₃
• 分子量: 372.344
• InChiKey: ZATBKOWQNOSWSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.58
• 重原子数：
  27.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  27.69
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  二苯甲酮腙 在 P-Rose Bengal manganese(IV) oxide 、 氧气 、 magnesium sulfate 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 3.67h， 生成 3,3-diphenyl-5-(4-(trifluoromethyl)phenyl)-1,2,4-trioxolane
  参考文献：
  名称：

  Electronic effects in the reaction of carbonyl oxides with aldehydes

  摘要：

  Electronic effects in the third step of the Criegee mechanism of ozonolysis, i.e., the reaction of a carbonyl oxide with a carbonyl compound, were studied by using a non-ozone source of carbonyl oxides as well as by an ozonolysis method. Benzophenone oxide, produced by photosensitized oxidation of diphenyldiazomethane or ozonolysis of tetraphenylethylene, was reacted with a series of para-substituted benzaldehydes. The relative rates of triaryl ozonide formation were treated with the Hammett relationship to give rho = 0.48 or 0.76, respectively, for the photooxidation and ozonolysis reactions. These results indicate that electron-withdrawing substituents in the aldehyde increase the rate of ozonide formation and are consistent with those reported earlier by Kuczkowski and co-workers for stilbene ozonide and with the long held view that ozonide formation involves reaction of a dipolar carbonyl oxide with the carbonyl partner.

  DOI：

  10.1021/jo00002a036

文献信息

• MURRAY, ROBERT W.;MORGAN, MICHAEL M., J. ORG. CHEM., 56,(1991) N, C. 684-687
  作者：MURRAY, ROBERT W.、MORGAN, MICHAEL M.

  DOI：——

  日期：——