| 1000988-09-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• CAS: 1000988-09-9
• 化学式: C₁₁H₁₆N₄S
• 分子量: 236.341
• InChiKey: SSGMJRDAWVEZRI-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  溴己烷 、 5-(2-噻吩基)-2H-四唑 在 sodium hydride 作用下， 以 四氢呋喃 、 二甲基亚砜 为溶剂， 反应 5.25h， 生成
  参考文献：
  名称：

  Synthesis and evaluation of novel heterocyclic MMP inhibitors

  摘要：

  A variety of novel heterocyclic compounds were synthesized and evaluated for MMP inhibition. Broad spectrum inhibition of MMPs 1, 2, 9, and 12 was found with pyridinone-based compounds while N-heterocyclic triazoles and tetrazoles were largely ineffective. A highly selective tetrazole inhibitor for MMP-2 was discovered. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2007.10.020