6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-(1H,3H)-quinazoline-2,4-dione | 164415-44-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-(1H,3H)-quinazoline-2,4-dione
• CAS: 164415-44-5
• 化学式: C₁₅H₇ClF₄N₂O₃
• 分子量: 374.679
• InChiKey: BHCDCSFYSSPJER-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-(1H,3H)-quinazoline-2,4-dione 、 碘甲烷 在 sodium hydride 作用下， 生成 6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-1,3-dimethyl-1H,3H-quinazoline-2,4-dione
  参考文献：
  名称：

  Synthesis of Novel Diphenyl Ether Herbicides

  摘要：

  The benzoxazine derivatives are a new chemical family of diphenyl ether herbicides, which exhibit a strong peroxidizing herbicidal activity on mono- and dicotyledonous species in preemergence and postemergence tests. Twenty derivatives were synthesized, and their herbicidal activity was determined to examine structure-activity relationships. Among the compounds investigated, it was found that the fluorine atom introduction into the trifluoromethylbenzene moiety together with an oxazine ring instead of a nitro group led to the most active herbicide.

  DOI：

  10.1021/jf00055a032
• 作为产物：
  描述：

  methyl 2-(carbamoylamino)-5-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>benzoate 在 sodium hydroxide 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以99%的产率得到6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-(1H,3H)-quinazoline-2,4-dione
  参考文献：
  名称：

  Synthesis of Novel Diphenyl Ether Herbicides

  摘要：

  The benzoxazine derivatives are a new chemical family of diphenyl ether herbicides, which exhibit a strong peroxidizing herbicidal activity on mono- and dicotyledonous species in preemergence and postemergence tests. Twenty derivatives were synthesized, and their herbicidal activity was determined to examine structure-activity relationships. Among the compounds investigated, it was found that the fluorine atom introduction into the trifluoromethylbenzene moiety together with an oxazine ring instead of a nitro group led to the most active herbicide.

  DOI：

  10.1021/jf00055a032