6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-3-(ethoxycarbonyl)-3-methyl-1,2,3,4-tetrahydroquinolin-2-one | 164415-40-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-3-(ethoxycarbonyl)-3-methyl-1,2,3,4-tetrahydroquinolin-2-one
• CAS: 164415-40-1
• 化学式: C₂₀H₁₆ClF₄NO₄
• 分子量: 445.798
• InChiKey: ZKCUZECDUBAQOU-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-3-(ethoxycarbonyl)-3-methyl-1,2,3,4-tetrahydroquinolin-2-one 在 sodium hydroxide 、 sodium hydride 作用下， 以 乙醇 为溶剂， 反应 2.33h， 生成 6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-1,3-dimethyl-1,2,3,4-tetrahydroquinolin-2-one
  参考文献：
  名称：

  Synthesis of Novel Diphenyl Ether Herbicides

  摘要：

  The benzoxazine derivatives are a new chemical family of diphenyl ether herbicides, which exhibit a strong peroxidizing herbicidal activity on mono- and dicotyledonous species in preemergence and postemergence tests. Twenty derivatives were synthesized, and their herbicidal activity was determined to examine structure-activity relationships. Among the compounds investigated, it was found that the fluorine atom introduction into the trifluoromethylbenzene moiety together with an oxazine ring instead of a nitro group led to the most active herbicide.

  DOI：

  10.1021/jf00055a032
• 作为产物：
  描述：

  3-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-6-nitrobenzyl bromide 在 镍 氢气 、 sodium hydride 作用下， 以 乙醇 为溶剂， 反应 2.0h， 生成 6-<2-chloro-6-fluoro-4-(trifluoromethyl)phenoxy>-3-(ethoxycarbonyl)-3-methyl-1,2,3,4-tetrahydroquinolin-2-one
  参考文献：
  名称：

  Synthesis of Novel Diphenyl Ether Herbicides

  摘要：

  The benzoxazine derivatives are a new chemical family of diphenyl ether herbicides, which exhibit a strong peroxidizing herbicidal activity on mono- and dicotyledonous species in preemergence and postemergence tests. Twenty derivatives were synthesized, and their herbicidal activity was determined to examine structure-activity relationships. Among the compounds investigated, it was found that the fluorine atom introduction into the trifluoromethylbenzene moiety together with an oxazine ring instead of a nitro group led to the most active herbicide.

  DOI：

  10.1021/jf00055a032