m-Chlor-α-ethylzimtsaeure | 53086-32-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: m-Chlor-α-ethylzimtsaeure
• 英文别名: 2-[(3-Chlorophenyl)methylidene]butanoic acid
• CAS: 53086-32-1
• 化学式: C₁₁H₁₁ClO₂
• 分子量: 210.66
• InChiKey: CMIKETAYGDWMJA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Novel 2'-C-methyl nucleoside derivatives
  申请人：Reddy Raja K.

  公开号：US20050182252A1

  公开（公告）日：2005-08-18

  Compounds of Formula I, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described:

  化合物I的配方、立体异构体以及其药用可接受的盐或前药，它们的制备以及它们用于治疗丙型肝炎病毒感染的用途被描述：
• NOVEL NUCLEOSIDE DERIVATIVES
  申请人：Metabasis Therapeutics, Inc.

  公开号：EP1781101A2

  公开（公告）日：2007-05-09
• NOVEL 2'-C-METHYL AND 4'-C-METHYL NUCLEOSIDE DERIVATIVES
  申请人：Merck & Co., Inc.

  公开号：EP1915053A2

  公开（公告）日：2008-04-30
• Novel 2'-C methyl nucleoside derivatives
  申请人：Erion D. Mark

  公开号：US20070179114A1

  公开（公告）日：2007-08-02

  Compounds of Formula I, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described:
• Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives
  申请人：Erion Mark D.

  公开号：US20090118223A1

  公开（公告）日：2009-05-07

  Novel 2′-C-methyl nucleoside 5′-monophosphate and 4′-C-methyl nucleoside 5′-monophosphate derivatives, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described.