Allyl-2-propen-1-sulfinat | 3359-75-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Allyl-2-propen-1-sulfinat
• 英文别名: Prop-2-enyl prop-2-ene-1-sulfinate
• CAS: 3359-75-9
• 化学式: C₆H₁₀O₂S
• 分子量: 146.21
• InChiKey: NXNSSVXQEWDXSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  45.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  烯丙醇 在 二氯化硫 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 Allyl-2-propen-1-sulfinat
  参考文献：
  名称：

  Organic Esters of Bivalent Sulfur. III. Sulfoxylates

  摘要：

  DOI：

  10.1021/jo01019a046

文献信息

• [EN] PROCESS FOR THE MANUFACTURE OF AJOENE DERIVATIVES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS D'AJOÈNE
  申请人：UNIV DANMARKS TEKNISKE

  公开号：WO2012076016A1

  公开（公告）日：2012-06-14

  The present invention relates to the compound (E,Z)-ajoene of formula (1) for use in treatment of bacterial infections. Another aspect of the present invention is a composition comprising (E,Z)-ajoene of formula (1) and at least one antibiotic. Yet another aspect of the invention relates to a method for manufacturing (E,Z) ajoene of formula (1) wherein the conformation of the internal C=C- bond can be either E or Z or a mixture thereof, said method comprising reacting allicin of formula (3) with an acid in the presence of a solvent to provide (E,Z ajoene) of formula (1) as defined above. Yet another aspect of the invention is (E,Z)-ajoene of formula 1 obtainable by the method described above.

  本发明涉及化合物（E,Z）-蒜烯（式1）的用途，用于治疗细菌感染。本发明的另一个方面是包含（E,Z）-蒜烯（式1）和至少一种抗生素的组合物。本发明的另一个方面涉及一种制备（E,Z）蒜烯（式1）的方法，其中内部C=C键的构象可以是E或Z或二者的混合物，所述方法包括在溶剂存在下将大蒜素（式3）与酸反应，以提供上述定义的（E,Z蒜烯）（式1）。本发明的另一个方面是通过上述描述的方法获得的（E,Z）-蒜烯（式1）。
• [EN] DIALLYLDISULPHIDE COMPOUNDS HAVING ANTILIPIDEMIC AND ANTIOXIDANT ACTIVITY<br/>[FR] COMPOSES DE DIALLYLDISULFURE PRESENTANT UNE ACTIVITE ANTILIPIDEMIQUE ET ANTIOXYDANTE
  申请人：DEPT OF SCIENCE AND TECHNOLOGY

  公开号：WO2004039771A1

  公开（公告）日：2004-05-13

  The present invention relates to a novel diallyldisulphide derivative having formula I as shown herebelow and their pharmaceutically acceptable salts; R-CH = CH - CH2-S-S-CH2-CH = CH-R (Formula I)wherein R=C6HnXp[when n = 3 to 5, p = 2 to 0; X=H, Cl, Br, F, CF3, CH3, CN, COOH, NO2, NH2, OH, OCmH2m+1(m = 1 to 8)]

  本发明涉及一种新型二烯丙基二硫化物衍生物，其具有下文所示的化学式I及其药学上可接受的盐；R-CH = CH - CH2-S-S- -CH = CH-R（化学式I）其中R=C6HnXp[当n = 3至5，p = 2至0；X=H，Cl，Br，F，CF3，CH3，CN，COOH，NO2，NH2，OH，OCmH2m+1（m = 1至8）]
• Use of extracts and compounds of allium-genus plants as preservatives in the food and agri-food industries
  申请人：Lara-Cambil Armando

  公开号：US20070160725A1

  公开（公告）日：2007-07-12

  The present invention relates to the use of extracts and compounds of plants from the Allium genus for the food and agrifood industry consisting of being used as food preservatives for humans and animals, plants being harvested or post-harvest plants, as well as for environmental disinfection, using thiosulfinates, thiosulfonates, ajoene, vinyl dithiins and products resulting from the decomposition of thiosulfinates.

  本发明涉及使用Allium属植物的提取物和化合物，用于食品和农业食品工业，作为人类和动物的食品防腐剂，包括采摘的或采后的植物，以及用于环境消毒，使用硫代磺酸盐，硫代磺酸酯，蒜辣素，乙烯二硫醚和硫代磺酸盐分解产物。
• PROCESS FOR THE MANUFACTURE OF AJOENE DERIVATIVES
  申请人：Bjarnsholt Thomas

  公开号：US20140303070A1

  公开（公告）日：2014-10-09

  The present invention relates to the compound (E,Z)-ajoene of formula (1) for use in treatment of bacterial infections. Another aspect of the present invention is a composition comprising (E,Z)-ajoene of formula (1) and at least one antibiotic. Yet another aspect of the invention relates to a method for manufacturing (E,Z) ajoene of formula (1) wherein the conformation of the internal C═C— bond can be either E or Z or a mixture thereof, said method comprising reacting allicin of formula (3) with an acid in the presence of a solvent to provide (E,Z ajoene) of formula (1) as defined above. Yet another aspect of the invention is (E,Z)-ajoene of formula 1 obtainable by the method described above.

  本发明涉及化合物（E，Z）-ajoene的公式（1），用于治疗细菌感染。本发明的另一方面是包含公式（1）的（E，Z）-ajoene和至少一种抗生素的组合物。本发明的另一方面涉及一种制备公式（1）的（E，Z）-ajoene的方法，其中内部C═C—键的构象可以是E或Z或它们的混合物，该方法包括在溶剂存在下反应公式（3）的大蒜素与酸，以提供上述定义的公式（1）的（E，Z）-ajoene。本发明的另一方面是通过上述描述的方法获得的公式1的（E，Z）-ajoene。
• Novel organic trithio oxides and method for the preparation thereof
  申请人：THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

  公开号：EP0185324A2

  公开（公告）日：1986-06-25

  This invention relates to novel organic trithio oxides of the formula: R1-X-R-X1-R1 wherein R is selected from X is selected from X' is selected from -S-S-, and each R' is independently selected from carboxyalkyl, alkoxy, alkylthio, amino, alkylamino and acyl substituted and unsubstituted lower alkyl, lower alkenyl, lower alkynyl, phenyl and lower alkylphenyl; provided when R is then R1 is not in both instances -CH2CH=CH2. This invention also relates to a method of preparing the above-identified compounds by heating and further oxidiz- ing various oxides of organic disulfides and to antithrombotic uses of the compounds.

  本发明涉及式如下的新型有机三硫氧化物：R1-X-R-X1-R1 其中 R 选自 X选自 X'选自-S-S-、 且每个 R'独立地选自羧基烷基、烷氧基、烷硫基、氨基、烷基氨基和酰基取代和未取代的低级烷基、低级烯基、低级炔基、苯基和低级烷基苯基；条件是当 R 为 则 R1 在两种情况下均不是- CH=CH2。 本发明还涉及一种通过加热和进一步氧化各种有机二硫化物来制备上述化合物的方法，以及这些化合物的抗血栓用途。