grammatophylloside A | 1425047-04-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: grammatophylloside A
• 英文别名: (2R)-2-benzyl-2-hydroxy-4-oxo-4-[[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methoxy]butanoic acid
• CAS: 1425047-04-6
• 化学式: C₂₄H₂₈O₁₁
• 分子量: 492.48
• InChiKey: CNSATNLYSTWACT-UINIGASKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  35
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  183
• 氢给体数：
  6
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  grammatophylloside A 在 水 、 sodium hydroxide 、 盐酸 作用下， 以 水 为溶剂， 反应 6.0h， 以87%的产率得到(2R)-2-benzyl-2-hydroxysuccinic acid
  参考文献：
  名称：

  Glucopyranosyloxybenzyl derivatives of (R)-2-benzylmalic acid and (R)-eucomic acid, and an aromatic glucoside from the pseudobulbs of Grammatophyllum speciosum

  摘要：

  Three new glucosyloxybenzyl derivatives of (R)-2-benzylmalic acid and of (R)-eucomic acid, grammatophyllosides A C, and a new phenolic glucoside, grammatophylloside D, were isolated from the pseudobulbs of Grammatophyllum speciosum along with cronupapine, vandateroside II, gastodin, vanilloloside, orcinol glucoside, and isovitexin. The structure elucidations of these compounds were based on analyses of physical and spectroscopic data, as well as chemical evidence. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2012.11.082

文献信息

• Glucopyranosyloxybenzyl derivatives of (R)-2-benzylmalic acid and (R)-eucomic acid, and an aromatic glucoside from the pseudobulbs of Grammatophyllum speciosum
  作者：Poolsak Sahakitpichan、Chulabhorn Mahidol、Wannaporn Disadee、Nitirat Chimnoi、Somsak Ruchirawat、Tripetch Kanchanapoom

  DOI：10.1016/j.tet.2012.11.082

  日期：2013.1

  Three new glucosyloxybenzyl derivatives of (R)-2-benzylmalic acid and of (R)-eucomic acid, grammatophyllosides A C, and a new phenolic glucoside, grammatophylloside D, were isolated from the pseudobulbs of Grammatophyllum speciosum along with cronupapine, vandateroside II, gastodin, vanilloloside, orcinol glucoside, and isovitexin. The structure elucidations of these compounds were based on analyses of physical and spectroscopic data, as well as chemical evidence. (C) 2012 Elsevier Ltd. All rights reserved.