Acetic acid (2S,3R,4S,5R,6R)-3,5-diacetoxy-2-[(2R,3R,4R,5R,6S)-5-acetoxy-6-((2R,3R,4R,6S)-4,6-dimethoxy-2-methyl-tetrahydro-pyran-3-yloxy)-4-methoxy-2-methyl-tetrahydro-pyran-3-yloxy]-6-acetoxymethyl-tetrahydro-pyran-4-yl ester | 89020-15-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Acetic acid (2S,3R,4S,5R,6R)-3,5-diacetoxy-2-[(2R,3R,4R,5R,6S)-5-acetoxy-6-((2R,3R,4R,6S)-4,6-dimethoxy-2-methyl-tetrahydro-pyran-3-yloxy)-4-methoxy-2-methyl-tetrahydro-pyran-3-yloxy]-6-acetoxymethyl-tetrahydro-pyran-4-yl ester
• CAS: 89020-15-5
• 化学式: C₃₁H₄₈O₁₈
• 分子量: 708.711
• InChiKey: QBQLECAKDCYGDE-MEXPWMLMSA-N

反应信息

• 作为产物：
  描述：

  乙酸酐 、 (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5R,6S)-6-((2R,3R,4R,6S)-4,6-Dimethoxy-2-methyl-tetrahydro-pyran-3-yloxy)-5-hydroxy-4-methoxy-2-methyl-tetrahydro-pyran-3-yloxy]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol 以 吡啶 为溶剂， 生成 Acetic acid (2S,3R,4S,5R,6R)-3,5-diacetoxy-2-[(2R,3R,4R,5R,6S)-5-acetoxy-6-((2R,3R,4R,6S)-4,6-dimethoxy-2-methyl-tetrahydro-pyran-3-yloxy)-4-methoxy-2-methyl-tetrahydro-pyran-3-yloxy]-6-acetoxymethyl-tetrahydro-pyran-4-yl ester
  参考文献：
  名称：

  萝摩科植物成分的研究。LVI。从Dregea volubilis（L.）BENTH分离新的抗肿瘤活性糖苷。

  摘要：

  从Dregea volubilis (L.) BENTH 的茎中分离到7 个新的苷类。根据化学和光谱证据推导出dregeoside Ap1 (1)、Ao1 (2)、Aa1 (3)、A11 (4)、C11 (5)、Ka1 (6) 和 Ka1 (7) 的结构：卓沃金配基 A 3-O-3-O-甲基-6-脱氧-β-D-别吡喃糖基-(1→4)-β-D-齐墩果吡喃糖基-(1→4)-β-D-吡喃吡喃糖基-(1→4) )-β-D-cymaropyranoside, drevogenin A 3-O-β-D-吡喃葡萄糖基-(1→4)-3-O-甲基-6-脱氧-β-D-别吡喃糖基-(1→4)-β- D-齐墩果吡喃糖基-(1→4)-β-D-西马吡喃糖基-(1→4)-β-D-西马吡喃糖苷，drevogenin A 3-O-3-O-甲基-6-脱氧-β-D-别吡喃糖基- (1→4)-β-D-吡喃葡萄糖基-(1→4)-β-D-吡喃葡萄糖苷，drevogenin A 3-O-β-D-吡喃葡萄糖基-(1→4)-3-O-甲基-6-脱氧-β-D-别吡喃糖基-(1→4)-β-D-吡喃吡喃糖基-(1→4)-β-D-吡喃吡喃糖苷，drevogenin C 3-O-β-D-吡喃葡萄糖基-(1→4)- 3-O-甲基-6-脱氧-β-D-吡喃糖基-(1→4)-β-D-吡喃糖基-(1→4)-β-D-吡喃糖苷，drebyssogenin K2 3-O-3-O-甲基-6-脱氧-β-D-别吡喃糖基-(1→4)-β-D-齐麻吡喃糖基-(1→4)-β-D-吡喃吡喃糖基-(1→4)-β-D-吡喃吡喃糖苷和drebyssogenin K2 分别为 3-O-3-O-甲基-6-脱氧-β-D-吡喃糖基-(1→4)-β-D-吡喃糖基-(1→4)-β-D-吡喃糖苷。其中，1和2对艾利希癌（实体型）有活性，后者对黑色素瘤B-16也有活性。

  DOI：

  10.1248/cpb.31.3971