2-acetyl-4-(4-bromobenzoyl)-3-methyl-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one | 1616512-18-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-acetyl-4-(4-bromobenzoyl)-3-methyl-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one
• CAS: 1616512-18-5
• 化学式: C₁₆H₁₄BrN₃O₃
• 分子量: 376.209
• InChiKey: HVLPJZHLECCVTG-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  4-(4-bromobenzoyl)-3-methyl-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one 、 乙酸酐 在 硫酸 作用下， 以53%的产率得到2-acetyl-4-(4-bromobenzoyl)-3-methyl-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one
  参考文献：
  名称：

  Three-Component Synthesis of 4-Aroyl-2(1),4,5,7-Tetrahydropyrazolo[3,4-b]Pyridin-6-Ones and Their Properties

  摘要：

  Inspired by the concept of multicomponent reactions, a novel one-pot synthesis involving arylglyoxals, 5-aminopyrazoles, and Meldrum's acid has been developed and employed for the creation of a small library of 4-aroyl-2(1),4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones. The alkylation, acylation, reduction, and oxidation reactions of 4-aroyl-3-methyl-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones have been studied.

  DOI：

  10.1007/s10593-014-1502-7