(E)-1-methyl-4-(1-phenylprop-1-en-2-yl)benzene | 916764-21-1

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物
• 英文名称: (E)-1-methyl-4-(1-phenylprop-1-en-2-yl)benzene
• 英文别名: 1-methyl-4-[(1E,3E)-3-methyl-4-phenylbuta-1,3-dienyl]benzene
• CAS: 916764-21-1
• 化学式: C₁₈H₁₈
• 分子量: 234.341
• InChiKey: UWUBUUCEYVOJSM-BMCDEEFISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-苯基-1-丙炔 、 4-甲苯硼酸 在 dicarbonylacetylacetonato rhodium (I) 作用下， 以 水 、 甲苯 为溶剂， 以91%的产率得到(E)-1-methyl-4-(1-phenylprop-1-en-2-yl)benzene
  参考文献：
  名称：

  A Homogeneous, Recyclable Polymer Support for Rh(I)-Catalyzed C–C Bond Formation

  摘要：

  A robust and practical polymer-supported, homogeneous, recyclable biphephos rhodium(I) catalyst has been developed for C-C bond formation reactions. Control of polymer molecular weight allowed tuning of the polymer solubility such that the polymer-supported catalyst is soluble in nonpolar solvents and insoluble in polar solvents. Using the supported rhodium catalysts, addition of aryl and vinylboronic acids to the electrophiles such as enones, aldehydes, N-sulfonyl aldimines, and alkynes occurs smoothly to provide products in high yields. Additions of terminal alkynes to enones and industrially relevant hydroformylation reactions have also been successfully carried out. Studies show that the leaching of Rh from the polymer support is low and catalyst recycle can be achieved by simple precipitation and filtration.

  DOI：

  10.1021/jo201476h