1-Allyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid | 53977-39-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-Allyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• 英文别名: 1-Allyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid；4-oxo-1-prop-2-enylquinoline-3-carboxylic acid
• CAS: 53977-39-2
• 化学式: C₁₃H₁₁NO₃
• 分子量: 229.235
• InChiKey: ORIUDVOSRDDPDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] C-7 ISOXAZOLINYL QUINOLONE/NAPHTHYRIDINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS<br/>[FR] DÉRIVÉS DE C-7 ISOXAZOLINYL QUINOLONE/NAPHTHYRIDINE CONVENANT COMME AGENTS ANTI-BACTÉRIENS
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2010093341A1

  公开（公告）日：2010-08-19

  The present invention relates to C-7 isoxazolyl quinoline/naphthyridine derivatives useful as antimicrobial compounds, pharmaceutical compositions comprising said derivatives and the use of said derivatives and pharmaceutical compositions as antimicrobial agents against pathogenic microorganisms, particularly against resistant microbes.

  本发明涉及C-7异噁唑基喹啉/萘啶衍生物，可用作抗微生物化合物，包括含有这些衍生物的药物组合物以及将这些衍生物和药物组合物用作抗病原微生物的抗微生物剂，特别是对抗耐药菌。
• [EN] 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES<br/>[FR] NAPHTYRIDONES ET QUINOLONES 7-AMINO ALKYLIDENYL-HETEROCYCLIQUES
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2005033108A1

  公开（公告）日：2005-04-14

  The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.

  本发明涉及具有如下式I所示结构的化合物，其中n、m、z、R、R2、R3、R4、R5、R6、A、E、X、Y、a和b如上所定义；或其光学异构体、对映异构体或对映体；以及其药学上可接受的盐、水合物或前药。
• C-7 Isoxazolinyl Quinolone / Naphthyridine Derivatives Useful as Antibacterial Agents
  申请人：Macielag Mark J.

  公开号：US20090029980A1

  公开（公告）日：2009-01-29

  The present invention relates to C-7 isoxazolyl quinoline/naphthyridine derivatives useful as antimicrobial compounds, pharmaceutical compositions comprising said derivatives and the use of said derivatives and pharmaceutical compositions as antimicrobial agents against pathogenic microorganisms, particularly against resistant microbes.

  本发明涉及C-7异噁唑基喹啉/萘啶衍生物，可用作抗微生物化合物，包括含有该衍生物的药物组合物以及将该衍生物和药物组合物用作抗病原微生物的抗微生物剂，特别是对抗耐药微生物。
• HAPTENS AND IMMUNOREACTIVE AGENTS AND USE THEREOF FOR PRODUCING FAMILY ANTIBODIES AND IMMUNOASSAYS FOR QUINOLONES
  申请人：Marco Colas Maria Pilar

  公开号：US20130273581A1

  公开（公告）日：2013-10-17

  The invention relates to haptens, immunogens and secondary immunoreactive agents, to the use thereof for producing wide-spectrum antibodies against quinolone-type antibiotics, to the application thereof to immunochemical analysis techniques, and to a kit enabling the detection of said antibiotics in biological samples from food products of animal origin.

  该发明涉及半抗原、免疫原和次级免疫反应剂，以及它们用于产生针对喹诺酮类抗生素的广谱抗体，应用于免疫化学分析技术，并且包括一种套件，可用于检测动物源食品生物样本中的该类抗生素。
• Antimicrobial quinolones, their compositions and uses
  申请人：The Procter & Gamble Company

  公开号：US20020049192A1

  公开（公告）日：2002-04-25

  Compounds having the general structure: 1 which are effective antimicrobial agents.

  具有一般结构1的化合物是有效的抗微生物药剂。