(+/-)-4-oxo-(4ar,8at)-decahydro-[1t]naphthoic acid | 23595-70-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (+/-)-4-oxo-(4ar,8at)-decahydro-[1t]naphthoic acid
• 英文别名: (+/-)-4-Oxo-(4ar,8at)-decahydro-[1t]naphthoesaeure；trans-anti-4-Oxo-1-carboxy-decalin；(1S,4aS,8aS)-4-oxo-2,3,4a,5,6,7,8,8a-octahydro-1H-naphthalene-1-carboxylic acid
• CAS: 23595-70-2；25920-48-3；103855-14-7
• 化学式: C₁₁H₁₆O₃
• 分子量: 196.246
• InChiKey: RXOMEMDYAKUOTE-CIUDSAMLSA-N

物化性质

• 熔点：
  153.2-154.7 °C(Solvent: Ethanol ; Hexane)
• 沸点：
  368.6±35.0 °C(Predicted)
• 密度：
  1.173±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (+/-)-4-oxo-(4ar,8at)-decahydro-[1t]naphthoic acid 在 盐酸 、 amalgamated zinc 作用下， 生成 (+/-)-(4arH,8atH)-Decahydro-1t-naphthoesaeure
  参考文献：
  名称：

  物质多环合成物—IX：d'α-十氢萘酮取代缩二烯的对数

  摘要：

  DOI：

  10.1016/0040-4020(58)88028-x
• 作为产物：
  描述：

  1-(1-氯-乙烯基)-环己烯 生成 (+/-)-4-oxo-(4ar,8at)-decahydro-[1t]naphthoic acid
  参考文献：
  名称：

  Stereochemistry of cyclic compounds

  摘要：

  DOI：

  10.1007/bf00907982

文献信息

• Synthesis of Substituted Cyclohexenones¹
  作者：Frederick C. Novello、Marcia E. Christy、James M. Sprague

  DOI：10.1021/ja01102a020

  日期：1953.3
• Total synthesis of yohimbine
  作者：Eugene E. Van Tamelen、Maurice Shamma、Albert W. Burgstahler、Joseph Wolinsky、Rudolph Tamm、Paul E. Aldrich

  DOI：10.1021/ja01054a021

  日期：1969.12
• Overexpression of the Arabidopsis thaliana MinD1 gene alters chloroplast size and number in transgenic tobacco plants
  作者：Randy Dinkins、Srinivasa M. Reddy、Mei Leng、Glenn B. Collins

  DOI：10.1007/s004250100605

  日期：2001.12

  The Arabidopsis thaliana (L.) Heynh. minD gene (AtMinD1) was isolated and constitutively expressed in tobacco (Nicotiana tabacum L.) plants using the CaMV 35S promoter. Confocal and electron-microscopic analysis of the AtMinD1 transgenic tobacco lines revealed that the chloroplasts were abnormally large and fewer in number compared with wild-type tobacco plants. The abnormal chloroplasts were less prevalent in guard cells than in mesophyll cells. Chloroplast and nuclear gene expression was not significantly different in AtMinD1-overexpressing plants relative to wild-type tobacco plants. Chloroplast DNA copy number was not affected, based on the relative level of the rbcL gene in transgenic plants. Transgenic tobacco plants constitutively overexpressing AtMinD1 were completely normal phenotypically with respect to growth and development, and also displayed normal photosynthetic electron transport rates. These results show that the Arabidopsis MinD1 gene also functions in a heterologous system and confirm the role of the MinD protein in regulation of chloroplast division.
• Chatterjee; Bhattacharyya, Journal of the Indian Chemical Society, 1958, vol. 35, p. 19,22
  作者：Chatterjee、Bhattacharyya

  DOI：——

  日期：——
• Nasarow et al., 1956, p. 1215,1218; engl. Ausg. S. 1241, 1244
  作者：Nasarow et al.

  DOI：——

  日期：——