methyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1--4)-O-(3,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1--3)-O-<2,4,6-tri-O-(p-bromobenzyl)-β-D-galactopyranosyl>-(1--4)-2,3,6-tri-O-(p-bromobenzyl)-β-D-glucopyranoside | 95918-66-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1--4)-O-(3,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1--3)-O-<2,4,6-tri-O-(p-bromobenzyl)-β-D-galactopyranosyl>-(1--4)-2,3,6-tri-O-(p-bromobenzyl)-β-D-glucopyranoside
• 英文别名: methyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1-4)-O-(3,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1-3)-O-<2,4,6-tri-O-(p-bromobenzyl)-β-D-galactopyranosyl>-(1-4)-2,3,6-tri-O-(p-bromobenzyl)-β-D-glucopyranoside
• CAS: 95918-66-4
• 化学式: C₈₇H₈₉Br₆NO₂₈
• 分子量: 2076.08
• InChiKey: FABYEJFEFRJVOC-XMKYKFPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.56
• 重原子数：
  122.0
• 可旋转键数：
  36.0
• 环数：
  12.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  324.4
• 氢给体数：
  0.0
• 氢受体数：
  28.0

反应信息

• 作为反应物：
  描述：

  methyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1--4)-O-(3,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1--3)-O-<2,4,6-tri-O-(p-bromobenzyl)-β-D-galactopyranosyl>-(1--4)-2,3,6-tri-O-(p-bromobenzyl)-β-D-glucopyranoside 在 palladium on activated charcoal 4 A molecular sieve 、 氢气 作用下， 以 1,4-二氧六环 、 甲醇 为溶剂， 反应 120.0h， 生成
  参考文献：
  名称：

  Glycosylation of lactose. Synthesis of methyl O-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-(1→3)-O-β-d-galactopyranosyl-(1→4)-β-d-glucopyranoside and methyl O-β-d-galactopyranosyl-(1→4)-O-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-(1→3)-O-β-d-galactopyranosyl- (1→4)-β-d-glucopyranoside

  摘要：

  DOI：

  10.1016/s0008-6215(00)90785-7
• 作为产物：
  描述：

  2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl(1<*>4)-2-deoxy-2-phthalimido-3,6-di-O-acetyl-β-D-glucopyranosyl chloride 、 methyl 2,3,6-tri-O-(p-bromobenzyl)-4-O-<2,4,6-tri-O-(p-bromobenzyl)-β-D-galactopyranosyl>-β-D-glucopyranoside 在 2,4,6-三甲基吡啶 、 4 A molecular sieve 、 silver trifluoromethanesulfonate 作用下， 以 二氯甲烷 为溶剂， 以68%的产率得到methyl O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1--4)-O-(3,6-di-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1--3)-O-<2,4,6-tri-O-(p-bromobenzyl)-β-D-galactopyranosyl>-(1--4)-2,3,6-tri-O-(p-bromobenzyl)-β-D-glucopyranoside
  参考文献：
  名称：

  Glycosylation of lactose. Synthesis of methyl O-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-(1→3)-O-β-d-galactopyranosyl-(1→4)-β-d-glucopyranoside and methyl O-β-d-galactopyranosyl-(1→4)-O-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-(1→3)-O-β-d-galactopyranosyl- (1→4)-β-d-glucopyranoside

  摘要：

  DOI：

  10.1016/s0008-6215(00)90785-7