2-(2,2,2-trifluoroethoxy)octane | 67696-31-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(2,2,2-trifluoroethoxy)octane
• 英文别名: 2-(2,2,2-trifluoro-ethoxy)-octane；2,2,2-Trifluorethyl-2'-octylether
• CAS: 67696-31-5
• 化学式: C₁₀H₁₉F₃O
• 分子量: 212.255
• InChiKey: NEHSLZLUJIPDPG-UHFFFAOYSA-N

物化性质

• 沸点：
  178-179 °C
• 密度：
  0.979±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  仲辛醇 、 2-重氮基-1,1,1-三氟乙烷 在 tetrafluoroboric acid 作用下， 以 氘代氯仿 为溶剂， 以100%的产率得到2-(2,2,2-trifluoroethoxy)octane
  参考文献：
  名称：

  Acid-catalyzed reactions of 2,2,2-trifluorodiazoethane for analysis of functional groups by fluorine-19 nuclear magnetic resonance spectrometry

  摘要：

  DOI：

  10.1021/ac00240a040

文献信息

• BIS(FLUOROALKOXY)TRIPHENYLPHOSPHORANES: PREPARATION AND REACTIONS
  作者：Toshio Kubota、Tomoya Kitazume、Nobuo Ishikawa

  DOI：10.1246/cl.1978.889

  日期：1978.8.5

  Bis(fluoroalkoxy)triphenylphosphoranes were prepared by the replacement of bromines of triphenylphosphine dibromide by fluoroalkoxides [C6H5C(CF3)2ONa, and CF3CH2ONa]. Alcohols and carboxylic acids readily reacted with Ph3P(OCH2CF3)2 to form corresponding 2,2,2-trifluoroethyl ethers and esters, respectively. Ph3P(OC(CF3)2C6H5]2, however, was so stable that it did not undergo reactions with these hydroxyl

  双（氟烷氧基）三苯基膦是通过用氟代醇盐 [C6H5C(CF3)2ONa 和 CH2ONa] 代替二溴化三苯基膦的溴来制备的。醇和羧酸很容易与 Ph3P(OCH2 )2 反应，分别形成相应的 2,2,2-三氟乙基醚和酯。然而，Ph3P(OC( )2C6H5]2 非常稳定，不会与这些羟基化合物发生反应。
• Novel synthetic reactions using bis(2,2,2-trifluoroethoxy)triphenylphosphorane
  作者：Toshio Kubota、Satoshi Miyashita、Tomoya Kitazume、Nobuo Ishikawa

  DOI：10.1021/jo01313a008

  日期：1980.12
• Enhancement of Reaction Efficiency by Functionalized Alcohols on Gold(I)-Catalyzed Intermolecular Hydroalkoxylation of Unactivated Olefins
  作者：Toshifumi Hirai、Akiyuki Hamasaki、Aki Nakamura、Makoto Tokunaga

  DOI：10.1021/ol9023166

  日期：2009.12.3

  Intermolecular hydroalkoxylation of unactivated olefins catalyzed by the combination of gold(I) and electron deficient phosphine ligands has been developed. Although pairings of unactivated olefins and common aliphatic alcohols gave unsatisfactory results In gold catalyzed hydroalkoxylations, the use of alcohol substrates bearing coordination functionalities such as halogen or alkoxy groups showed great improvement of reactivity.
• KUBOTA TOSHIO; MIYASHITA SATOSHI; KITAZUME TOMOYA; ISHIKAWA NOBUO, J. ORG. CHEM., 1980, 45, NO 25, 5052-5057
  作者：KUBOTA TOSHIO、 MIYASHITA SATOSHI、 KITAZUME TOMOYA、 ISHIKAWA NOBUO

  DOI：——

  日期：——