(2Z,4Z)-2,3,4,5-Tetrapropyl-hexa-2,4-dienedial | 863505-57-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2Z,4Z)-2,3,4,5-Tetrapropyl-hexa-2,4-dienedial
• 英文别名: (2Z,4Z)-2,3,4,5-tetrapropylhexa-2,4-dienedial
• CAS: 863505-57-1
• 化学式: C₁₈H₃₀O₂
• 分子量: 278.435
• InChiKey: MAXVDHXWYTXZBZ-IQRFGFHNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  20
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (2Z,4Z)-2,3,4,5-Tetrapropyl-hexa-2,4-dienedial 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 反应 1.0h， 以81%的产率得到(2Z,4Z)-2,3,4,5-Tetrapropyl-hexa-2,4-diene-1,6-diol
  参考文献：
  名称：

  Concise synthesis of multiply substituted stereodefined cis,cis-2,4-diene-1,6-dials, cis,cis-2,4-diene-1,6-diols and further applications

  摘要：

  Reactions of 1,4-dilithio-1,3-dienes with DMF afforded multiply substituted stereodefined cis,cis-2,4-diene-1,6-dials in high yields. Treatment of these 1,6-dials with LiAlH4 or RLi resulted in the formation of their corresponding 1,6-diols. These bifunctional compounds, cis,cis-2,4-diene-1,6-dials and -1,6-diols are otherwise not readily available. Further reaction of these 1,6-diols with an aldehyde catalyzed by strong acids led to the formation of oxacycles of novel structures. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.06.003
• 作为产物：
  描述：

  N,N-二甲基甲酰胺 、 1,4-dilithio-1,2,3,4-tetrapropyl-1,3-butaidiene 以 乙醚 为溶剂， 反应 1.0h， 以51%的产率得到(2Z,4Z)-2,3,4,5-Tetrapropyl-hexa-2,4-dienedial
  参考文献：
  名称：

  Concise synthesis of multiply substituted stereodefined cis,cis-2,4-diene-1,6-dials, cis,cis-2,4-diene-1,6-diols and further applications

  摘要：

  Reactions of 1,4-dilithio-1,3-dienes with DMF afforded multiply substituted stereodefined cis,cis-2,4-diene-1,6-dials in high yields. Treatment of these 1,6-dials with LiAlH4 or RLi resulted in the formation of their corresponding 1,6-diols. These bifunctional compounds, cis,cis-2,4-diene-1,6-dials and -1,6-diols are otherwise not readily available. Further reaction of these 1,6-diols with an aldehyde catalyzed by strong acids led to the formation of oxacycles of novel structures. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.06.003

文献信息

• Concise synthesis of multiply substituted stereodefined cis,cis-2,4-diene-1,6-dials, cis,cis-2,4-diene-1,6-diols and further applications
  作者：Guoliang Mao、Congyang Wang、Jinglong Chen、Ayako Muramatsu、Zhenfeng Xi

  DOI：10.1016/j.tetlet.2005.06.003

  日期：2005.8

  Reactions of 1,4-dilithio-1,3-dienes with DMF afforded multiply substituted stereodefined cis,cis-2,4-diene-1,6-dials in high yields. Treatment of these 1,6-dials with LiAlH4 or RLi resulted in the formation of their corresponding 1,6-diols. These bifunctional compounds, cis,cis-2,4-diene-1,6-dials and -1,6-diols are otherwise not readily available. Further reaction of these 1,6-diols with an aldehyde catalyzed by strong acids led to the formation of oxacycles of novel structures. (c) 2005 Elsevier Ltd. All rights reserved.