ethyl 4-(3-ethoxy-4-hydroxyphenyl)-2-methyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate | 1373710-20-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: ethyl 4-(3-ethoxy-4-hydroxyphenyl)-2-methyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate
• CAS: 1373710-20-3
• 化学式: C₂₁H₂₃NO₅
• 分子量: 369.417
• InChiKey: CFDCJOATYOUUOG-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  ethyl 4-(3-ethoxy-4-hydroxyphenyl)-2-methyl-5-oxo-1,4,6,7,8-pentahydroquinoline-3-carboxylate 在 graphite oxide 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以92%的产率得到ethyl 4-(3-ethoxy-4-hydroxyphenyl)-2-methyl-5-oxo-5,6,7,8-tetrahydroquinoline-3-carboxylate
  参考文献：
  名称：

  Graphite oxide mediated oxidative aromatization of 1,4-dihydropyridines into pyridine derivatives

  摘要：

  A new approach utilizing graphite oxide as an oxidizing agent is applied for the oxidative aromatization of 1,4-dihydropyridines. Graphite oxide efficiently aromatized Hantzsch 1,4-dihydropyridines into their corresponding pyridine derivatives in excellent yields. The reaction was carried out in toluene at 100 degrees C. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.03.026