(R)-1-((3aS,4R,6R,6aS)-6-Allyloxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-ethane-1,2-diol | 222845-99-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (R)-1-((3aS,4R,6R,6aS)-6-Allyloxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-ethane-1,2-diol
• CAS: 222845-99-0
• 化学式: C₁₂H₂₀O₆
• 分子量: 260.287
• InChiKey: ZCYRVPBWEILCIK-SAVGLBRCSA-N

反应信息

• 作为反应物：
  描述：

  (R)-1-((3aS,4R,6R,6aS)-6-Allyloxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-ethane-1,2-diol 在 sodium hydride 、 三氟乙酸 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 生成 (R)-2-((3aS,4R,6R,6aS)-6-Allyloxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-2-(4-methoxy-benzyloxy)-ethanol
  参考文献：
  名称：

  Regioselective deprotection of p-methoxybenzyl ethers of furanose derivatives

  摘要：

  Reaction of per-p-methoxybenzylated hexofuranoses and pentofuranoses with either a catalytic amount of tin chloride dihydrate (SnCl2. 2H(2)O) or 0.5-10% solution of trifluoroacetic acid in dichloromethane afforded regioselectively the corresponding monosaccharide derivatives having a single free hydroxyl group at C(5) in good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00396-2
• 作为产物：
  描述：

  (3aS,4R,6R,6aS)-4-Allyloxy-6-[(R)-1,2-bis-(4-methoxy-benzyloxy)-ethyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 以8%的产率得到(R)-1-((3aS,4R,6R,6aS)-6-Allyloxy-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-ethane-1,2-diol
  参考文献：
  名称：

  Regioselective deprotection of p-methoxybenzyl ethers of furanose derivatives

  摘要：

  Reaction of per-p-methoxybenzylated hexofuranoses and pentofuranoses with either a catalytic amount of tin chloride dihydrate (SnCl2. 2H(2)O) or 0.5-10% solution of trifluoroacetic acid in dichloromethane afforded regioselectively the corresponding monosaccharide derivatives having a single free hydroxyl group at C(5) in good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00396-2