1-methoxymethyl-3-methylimidazolium chloride | 36443-88-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 1-methoxymethyl-3-methylimidazolium chloride
• 英文别名: 3-(methoxymethyl)-1-methylimidazolium chloride；MeOMImCl；1-(methoxymethyl)-3-methylimidazol-3-ium;chloride
• CAS: 36443-88-6
• 化学式: C₆H₁₁N₂O*Cl
• 分子量: 162.619
• InChiKey: NTDBGKNFROYFME-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.08
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-methoxymethyl-3-methylimidazolium chloride 、 三氟甲基三氟硼酸钾 以 水 为溶剂， 以60%的产率得到1-methoxymethyl-3-methylimidazolium trifluoromethyltrifluoroborate
  参考文献：
  名称：

  低熔点，低粘度，疏水性离子液体：1-烷基（烷基醚）-3-甲基咪唑全氟烷基三氟硼酸酯。

  摘要：

  一系列22个疏水离子液体，即1-烷基（烷基醚）-3-甲基咪唑鎓（[C（m）mim] +或[C（m）O（n）mim] +；其中Cm为1-烷基， Cm = nCmH（2m + 1），m = 1-4和6; C（m）O（n）是1-烷基醚，C2O1 = CH3OCH2，C3O1 = CH3OCH2CH2，和C5O2 = CH3（OCH2CH2）2）全氟烷基三氟硼酸酯（ [RFBF3]-，RF ＝ CF3，C2F5，nC3F7，nC4F9）已经制备并表征。已确定了这些盐的一些重要物理化学性质，包括熔点，玻璃化转变，粘度，密度，离子电导率，热和电化学稳定性，并将其与已报道的基于[BF4]（-）的盐进行了比较。讨论了咪唑阳离子和全氟烷基三氟硼酸根（[RFBF3]-）阴离子的结构变化对上述理化性质的影响。

  DOI：

  10.1002/chem.200400533
• 作为产物：
  描述：

  N-甲基咪唑 、 氯甲基甲基醚 以99 %的产率得到1-methoxymethyl-3-methylimidazolium chloride
  参考文献：
  名称：

  用于多用途混合缩醛的路易斯酸催化合成烷氧基甲基卤化物；范围和限制

  摘要：

  摘要：本文详细介绍了路易斯酸催化制备结构异构的烷氧甲基卤代物的过程。评估了一系列具有不同卤化试剂的路易斯酸对双烷氧甲烷的裂解，发现几种易得的路易斯酸表现出高催化潜力。SOCl2与MgCl2的组合被发现是在无溶剂条件下制备结构多样的烷氧甲基卤代物最好的选择之一。该方法的有效性已被证明，可以通过烷氧甲基化磷、硫、氮和含氧亲核试剂来获得广泛的混合缩醛。本方法具有简单性、普适性、快速性和试剂的可获得性等显著优点。

  DOI：

  10.2174/1570178619666220112105145

文献信息

• The solubility and recrystallization of 1,3,5-triamino-2,4,6-trinitrobenzene in a 3-ethyl-1-methylimidazolium acetate–DMSO co-solvent system
  作者：T. Yong-Jin Han、Philip F. Pagoria、Alexander E. Gash、Amitesh Maiti、Christine A. Orme、Alexander R. Mitchell、Laurence E. Fried

  DOI：10.1039/b810109d

  日期：——

  Ionic liquids have previously been shown to dissolve strong inter- and intramolecular hydrogen-bonded solids, including natural fibers. Much of this solubility is attributed to the anions in ionic liquids, which can disrupt hydrogen bonding. We have studied the solubility and recrystallization of 1,3,5-triamino-2,4,6-trinitrobenzene (TATB), a very strong inter- and intramolecular hydrogen-bonded solid, in various ionic liquid solvent systems. We discovered that acetate-based ionic liquids were the best solvents for dissolving TATB, while other anions, such as Cl−, HSO4− and NO3− showed moderate improvements in the solubility compared to conventional organic solvents. Ionic liquid–DMSO co-solvent systems were also investigated for dissolving and recrystallizing TATB.

  离子液体此前已被证明可以溶解强分子间和分子内氢键固体，包括天然纤维。这种溶解度很大程度上归因于离子液体中的阴离子，它可以破坏氢键。我们研究了 1,3,5-三氨基-2,4,6-三硝基苯 (TATB)（一种非常强的分子间和分子内氢键固体）在各种离子液体溶剂体系中的溶解度和重结晶。我们发现醋酸盐离子液体是溶解TATB的最佳溶剂，而其他阴离子，如Cl-、HSO4-和NO3-与传统有机溶剂相比，溶解度略有改善。还研究了离子液体-DMSO 共溶剂系统用于溶解和重结晶 TATB。
• Ionic liquids as solvents
  申请人：Pagoria Philip F.

  公开号：US20090012297A1

  公开（公告）日：2009-01-08

  A method in one embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having a fluoride anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of about 90° C. or less during the contacting. A method in another embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having an acetate or formate anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of less than about 90° C. during the contacting. A method for purifying a strongly hydrogen bonded organic material according to one another embodiment includes dissolving a strongly hydrogen bonded organic material, selected from a group consisting of 1,3,5-triamino-2,4,6-trinitrobenzene and 2,6-diamino-3,5-dinitropyrazine-1-oxide, in a solution comprising an ionic liquid, the ionic liquid having an anion selected from a group consisting of a fluoride anion, an acetate anion, and a formate anion; maintaining the solution at a temperature of about 70° C. or less during the contacting; and recrystallizing the strongly hydrogen bonded organic material.

  一种实施例的方法包括将强氢键有机材料与具有氟化物阴离子的离子液体接触以使强氢键有机材料溶解；并在接触期间将离子液体保持在约90°C或更低的温度。另一实施例的方法包括将强氢键有机材料与具有醋酸盐或甲酸盐阴离子的离子液体接触以使强氢键有机材料溶解；并在接触期间将离子液体保持在约90°C以下的温度。根据另一实施例的强氢键有机材料纯化方法包括将强氢键有机材料（从由1,3,5-三氨基-2,4,6-三硝基苯和2,6-二氨基-3,5-二硝基吡嗪-1-氧化物组成的组中选择）溶解在包括离子液体的溶液中，所述离子液体具有从氟化物阴离子、醋酸盐阴离子和甲酸盐阴离子组成的阴离子；在接触期间将溶液保持在约70°C或更低的温度；并重新结晶强氢键有机材料。
• Methods of using ionic liquids having a fluoride anion as solvents
  申请人：Lawrence Livermore National Security, LLC

  公开号：US08071813B2

  公开（公告）日：2011-12-06

  A method in one embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having a fluoride anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of about 90° C. or less during the contacting. A method in another embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having an acetate or formate anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of less than about 90° C. during the contacting.

  一种实施例中的方法包括将强氢键有机材料与具有氟化物阴离子的离子液体接触以溶解强氢键有机材料；并在接触期间将离子液体保持在约90°C或更低的温度。另一种实施例中的方法包括将强氢键有机材料与具有乙酸盐或甲酸盐阴离子的离子液体接触以溶解强氢键有机材料；并在接触期间将离子液体保持在低于约90°C的温度。
• An Operationally Simple and Scalable Approach to Functionalized Ionic Liquids from Phosphonium and N-Heterocyclic Halide Salts
  作者：Brandon Ashfeld、Christopher Meyer、Monika Vogt、James Catalino

  DOI：10.1055/s-0033-1338806

  日期：——

  An approach toward the synthesis of N-heterocyclic anionic ionic liquids is described. The ionic liquids are readily obtained by the treatment of the sodium salt of the parent N-heterocycle with the halide salt of the desired cation. Good to excellent yields (62-99%) of the corresponding ionic liquids are obtained without the use of excessive materials and time associated with conventional methods for synthesizing heterocyclic based ionic liquids.
• US8071813B2
  申请人：——

  公开号：US8071813B2

  公开（公告）日：2011-12-06