4-(4-庚基苯基)-4-氧代丁酸 | 64779-09-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-(4-庚基苯基)-4-氧代丁酸
• 英文名称: 3-(4-heptylbenzoyl)propionic acid
• 英文别名: 4-(4-Heptylphenyl)-4-oxobutanoic acid
• CAS: 64779-09-5
• 化学式: C₁₇H₂₄O₃
• mdl: MFCD00173761
• 分子量: 276.376
• InChiKey: LRAJLMGRXDVQNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  20
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(4-庚基苯基)-4-氧代丁酸 生成 ethyl 4-(4-heptylphenyl)-4-hydroxybutanoate
  参考文献：
  名称：

  Cis-gamma-butyrolactone compounds and composition comprising the same

  摘要：

  公开号：

  EP0488682B1
• 作为产物：
  描述：

  丁二酸酐 、 庚基苯 生成 4-(4-庚基苯基)-4-氧代丁酸
  参考文献：
  名称：

  Cis-gamma-butyrolactone compounds and composition comprising the same

  摘要：

  公开号：

  EP0488682B1

文献信息

• Methods and compositions for determining the sequence of nucleic acid molecules
  申请人：QIAGEN Genomics, Inc.

  公开号：US20040115694A1

  公开（公告）日：2004-06-17

  Methods and compounds, including compositions therefrom, are provided for determining the sequence of nucleic acid molecules. The methods permit the determination of multiple nucleic acid sequences simultaneously. The compounds are used as tags to generate tagged nucleic acid fragments which are complementary to a selected target nucleic acid molecule. Each tag is correlative with a particular nucleotide and, in a preferred embodiment, is detectable by mass spectrometry. Following separation of the tagged fragments by sequential length, the tags are cleaved from the tagged fragments. In a preferred embodiment, the tags are detected by mass spectrometry and the sequence of the nucleic acid molecule is determined therefrom. The individual steps of the methods can be used in automated format, e.g., by the incorporation into systems.

  提供了用于确定核酸分子序列的方法和化合物，包括从中制备的组合物。该方法允许同时确定多个核酸序列。这些化合物被用作标记，以生成与所选目标核酸分子互补的带标记的核酸片段。每个标记与特定的核苷酸相关，在优选实施例中，可以通过质谱法检测到。在通过顺序长度分离带标记的片段后，将从带标记的片段中切除标记。在优选实施例中，通过质谱法检测标记，并从中确定核酸分子的序列。该方法的各个步骤可以以自动化格式使用，例如通过纳入系统中。
• Lactone compound and composition comprising the same
  申请人：Chisso Corporation

  公开号：US05256330A1

  公开（公告）日：1993-10-26

  A novel lactone compound exhibiting a larger spontaneous polarization value when added to ferroelectric liquid crystal compositions as a basic substance, than those of so far known lactone compounds, and yet having a relatively low viscosity, and a liquid crystal composition comprising the compound, and further a liquid crystal element using the same are provided, the lactone compound being expressed by the formula ##STR1## wherein R.sup.1 is a linear or branched alkyl group or alkoxy group of 1-15C, R.sup.2 is a linear or branched alkyl group of 1-16C, --A-- is single bond, 1,4-phenylene group or 1,4-cyclohexylene group and * is an asymmetric carbon atom.

  提供了一种新型内酯化合物，当作为基础物质添加到铁电液晶组合物中时，其自发极化值比迄今为止已知的内酯化合物更大，同时具有相对较低的粘度，以及包含该化合物的液晶组成物和使用相同的液晶元件。该内酯化合物由以下式子表示：##STR1##其中，R1是1-15C的线性或支链烷基或烷氧基，R2是1-16C的线性或支链烷基，-A-是单键，1,4-苯基或1,4-环己基，*是一个不对称碳原子。
• METHODS AND COMPOSITIONS FOR ANALYZING NUCLEIC ACID MOLECULES UTILIZING SIZING TECHNIQUES
  申请人：Van Ness Jeffrey

  公开号：US20060057566A1

  公开（公告）日：2006-03-16

  Tags and linkers specifically designed for a wide variety of nucleic acid reactions are disclosed, which are suitable for a wide variety of nucleic acid reactions wherein separation of nucleic acid molecules based upon size is required.

  本发明揭示了专门设计用于各种核酸反应的标签和连接剂，适用于需要基于大小分离核酸分子的各种核酸反应。
• Methods and compositions for detecting binding of ligand pair using non-fluorescent label
  申请人：Rapigene, Inc.

  公开号：EP0962464A2

  公开（公告）日：1999-12-08

  Methods are provided for detecting the binding of a first member to a second member of a ligand pair, comprising the steps of (a) combining a set of first tagged members with a biological sample which may contain one or more second members, under conditions, and for a time sufficient to permit binding of a first member to a second member, wherein said tag is correlative with a particular first member and detectable by non-fluorescent spectrometry, or potentiometry; (b) separating bound first and second members from unbound members; (c) cleaving the tag from the tagged first member; and (d) detecting the tag by non-fluorescent spectrometry, or potentiometry, and therefrom detecting the binding of the first member to the second member.

  本发明提供了检测配体对中第一成员与第二成员结合的方法，包括以下步骤：(a) 在足以允许第一成员与第二成员结合的条件和时间下，将一组第一标记成员与可能含有一个或多个第二成员的生物样品结合，其中所述标记与特定的第一成员相关，并可通过非荧光光谱法或电位计法检测；(b) 将结合的第一和第二成员与未结合的成员分离； (c) 从标记的第一成员上裂解标记；以及 (d) 通过非荧光光谱法或电位测定法检测标记，并由此检测第一成员与第二成员的结合情况。
• Methods and compositions for enhancing sensitivity in the analysis of biological-based assays
  申请人：QIAGEN Genomics, Inc.

  公开号：US20030077595A1

  公开（公告）日：2003-04-24

  Methods are provided for detecting the binding of a first member to a second member of a ligand pair, comprising the steps of (a) combining a set of first tagged members with a biological sample which may contain one or more second members, under conditions, and for a time sufficient to permit binding of a first member to a second member, wherein said tag is correlative with a particular first member and detectable by non-fluorescent spectrometry, or potentiometry, (b) separating bound first and second members from unbound members, (c) cleaving the tag from the tagged first member, and (d) detecting the tag by non-fluorescent spectrometry, or potentiometry, and therefrom detecting the binding of the first member to the second member .

  本发明提供了检测配体对中第一成员与第二成员结合的方法，包括以下步骤：(a) 在足以允许第一成员与第二成员结合的条件和时间下，将一组第一标记成员与可能含有一个或多个第二成员的生物样品结合、其中所述标记与特定的第一成员相关，并可通过非荧光光谱法或电位计法检测；(b) 将结合的第一和第二成员与未结合的成员分离；(c) 从标记的第一成员上裂解标记；(d) 通过非荧光光谱法或电位计法检测标记，并由此检测第一成员与第二成员的结合情况。