(S)-4-acetyl-3,4-dimethyl-2-cyclohexenone | 71379-66-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-4-acetyl-3,4-dimethyl-2-cyclohexenone
• 英文别名: (4S)-4-acetyl-3,4-dimethylcyclohex-2-en-1-one
• CAS: 71379-66-3
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: RNMROYKUHOFGKN-JTQLQIEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-acetyl-3-methyl-2,6-heptanedione 在 L-prolinamide derived sulfonylated polystyrene 作用下， 以 neat (no solvent) 为溶剂， 反应 312.0h， 以50%的产率得到
  参考文献：
  名称：

  Novel supported and unsupported prolinamides as organocatalysts for enantioselective cyclization of triketones

  摘要：

  A novel prolylsulfonamide derived from ethylene diamine and its supported counterpart has been prepared and tested as enantioselective intramolecular aldol reaction of cyclic and acyclic triketones. Good to excellent yields and enantioselectivities have been obtained in water and under solvent free conditions. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.03.123