1-Bromocyclohexan-1-OL | 74098-24-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-Bromocyclohexan-1-OL
• CAS: 74098-24-1
• 化学式: C₆H₁₁BrO
• 分子量: 179.05
• InChiKey: HGFAPMFYZRDEQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-Bromocyclohexan-1-OL 在 氢溴酸 、 lithium bromide 作用下， 以 二氯甲烷 、 水 为溶剂， 生成 1-溴-1-甲基环己烷
  参考文献：
  名称：

  空气气氛下球磨镍催化 1,3-烯炔的还原 1,4-烷基化

  摘要：

  开发了一种球磨机镍催化的 1,3-烯炔与有机溴化物的 1,4-烷基芳基化反应，为组装四取代丙二烯提供了一种通用方法。这种方法是第一种基于球磨的远程自由基偶联方法，克服了传统溶液相方法的局限性，例如需要空气和湿度敏感的试剂、使用大量溶剂以及延长反应时间。鉴于基于球磨的自由基还原偶联反应的出色性能，我们预计可持续和高效的合成方法将取得进一步进展。

  DOI：

  10.1021/acs.orglett.4c02729

文献信息

• METHOD FOR PRODUCING CYCLIC CARBONATE
  申请人：NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

  公开号：US20160145234A1

  公开（公告）日：2016-05-26

  Provided is a method for producing a cyclic carbonate obtained by reacting epoxide and carbon dioxide, the method being capable of efficiently producing a cyclic carbonate at a high conversion rate and a high yield, in which degradation of the catalyst over time is suppressed and catalytic activity hardly decreases. A method for producing a cyclic carbonate by reacting epoxide and carbon dioxide in the presence of a quaternary onium salt selected from the group consisting of a quaternary ammonium salt having a halogenated anion as a counter ion and a quaternary phosphonium salt having a halogenated anion as a counter ion, or in the presence of a solid catalyst obtained by immobilizing the quaternary onium salt onto a carrier, wherein an organohalogen compound containing at least one halogen atom in one molecule is added to the reaction system.

  提供了一种生产环状碳酸酯的方法，该方法通过反应环氧化物和二氧化碳获得，能够高效地以高转化率和高产率生产环状碳酸酯，同时抑制催化剂随时间降解并且催化活性几乎不会下降。在存在从属于具有卤素阴离子作为对离子的季铵盐和具有卤素阴离子作为对离子的季膦盐中选择的季铵盐，或者存在通过将季铵盐固定在载体上而获得的固体催化剂的情况下，通过在反应体系中添加含有至少一个卤素原子的有机卤素化合物来生产环状碳酸酯的方法。
• METHOD FOR PRODUCING CARBOXYLIC ACID
  申请人：National Institute of Advanced Industrial Science and Technology

  公开号：EP1544190A1

  公开（公告）日：2005-06-22

  The present invention provides a safe, convenient and efficient method for producing carboxylic acid by a reaction of alicyclic alcohol with an aqueous hydrogen peroxide to thereby obtain carboxylic acid in high yield from alicyclic alcohol or alicyclic ketone under mild reaction conditions, wherein the reaction operation is simple and easy, a step for removing solvent after completion of the reaction is not necessary and influence and toxicity upon the environment and human body are markedly small. In order to provide it, an oily alicyclic alcohol is allowed to react with an aqueous hydrogen peroxide in the presence of a catalyst containing a metal compound belonging to Group 6 of the Periodic Table in a heterogeneous solution system.

  本发明提供了一种安全、方便、高效的生产羧酸的方法，该方法通过脂环醇与过氧化氢水溶液反应，从而在温和的反应条件下，从脂环醇或脂环酮中高产率地获得羧酸，反应操作简单易行，反应完成后无需去除溶剂的步骤，对环境和人体的影响和毒性明显较小。为了实现这一目标，需要在一个异相溶液体系中，在含有元素周期表第 6 族金属化合物的催化剂存在下，使油性脂环醇与过氧化氢水溶液发生反应。
• CYCLIC AMINE COMPOUND AND MITICIDE
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2540719A1

  公开（公告）日：2013-01-02

  The present invention provides a cyclic amine compound represented by formula (I) (in formula (I), Cy1 and Cy2 independently represent a C6-10 aryl group or a heterocyclyl group; R1a to R5a independently represent a hydrogen atom or an unsubstituted or substituted C1-6 alkyl group; R10, R", R20 and R21 independently represent an unsubstituted or substituted C1-6 alkyl group, an unsubstituted or substituted C1-6 alkoxy group, a halogen atom or the like; m, n, p, and r each represent an integer of 0 to 5; and Y represents an oxygen atom or the like) or salt thereof, and an acaricide including the same.

  本发明提供了一种由式(I)代表的环胺化合物（在式(I)中，Cy1和Cy2独立地代表C6-10芳基或杂环基；R1a至R5a独立地代表氢原子或未取代或取代的C1-6烷基；R10、R"、R20和R21独立地代表未取代或取代的C1-6烷基、未取代或取代的C1-6烷氧基、卤素原子或类似物；m、n、p和r各自代表0至5的整数；以及Y代表氧原子或类似物）或其盐，以及包括相同内容的杀螨剂。
• PYRIDINE COMPOUND AND AGRICULTURAL FUNGICIDE
  申请人：Nippon Soda Co., Ltd.

  公开号：EP2876106A1

  公开（公告）日：2015-05-27

  The present invention provides an agricultural fungicide having definitive effects which can be safely used, and a pyridine compound or salts thereof useful as an active ingredient of an agricultural fungicide. The pyridine compound or salts thereof of the present invention are represented by the following formula. In the formula, R1 represents a formyl group or the like, R2 represents a hydrogen bond or the like, each of R3, R4, and R5 independently represents a hydrogen atom, E represents a phenyl group or the like, A represents a halogen atom, and n is any integer of 0 to 5.

  本发明提供了一种可安全使用的具有确切效果的农用杀菌剂，以及一种可用作农用杀菌剂活性成分的吡啶化合物或其盐类。本发明的吡啶化合物或其盐由下式表示。式中，R1代表甲酰基或类似物，R2代表氢键或类似物，R3、R4和R5各自独立地代表氢原子，E代表苯基或类似物，A代表卤素原子，n为0至5的任意整数。
• METHOD FOR MANUFACTURING CYCLIC CARBONATE
  申请人：National Institute of Advanced Industrial Science and Technology

  公开号：EP3023418A1

  公开（公告）日：2016-05-25

  Provided is a method for producing a cyclic carbonate obtained by reacting epoxide and carbon dioxide, the method being capable of efficiently producing a cyclic carbonate at a high conversion rate and a high yield, in which degradation of the catalyst over time is suppressed and catalytic activity hardly decreases. A method for producing a cyclic carbonate by reacting epoxide and carbon dioxide in the presence of a quaternary onium salt selected from the group consisting of a quaternary ammonium salt having a halogenated anion as a counter ion and a quaternary phosphonium salt having a halogenated anion as a counter ion, or in the presence of a solid catalyst obtained by immobilizing the quaternary onium salt onto a carrier, wherein an organohalogen compound containing at least one halogen atom in one molecule is added to the reaction system.

  本发明提供了一种通过环氧化物和二氧化碳反应获得环状碳酸盐的生产方法，该方法能够以高转化率和高产率高效生产环状碳酸盐，其中催化剂随时间推移的降解受到抑制，催化活性几乎没有降低。 一种生产环碳酸盐的方法，该方法通过环氧化物和二氧化碳在季鎓盐的存在下或在通过将季鎓盐固定在载体上获得的固体催化剂的存在下反应环碳酸盐，该季鎓盐选自具有卤化阴离子作为反离子的季铵盐和具有卤化阴离子作为反离子的季鏻盐组成的组，其中在一个分子中含有至少一个卤原子的有机卤化合物被添加到反应体系中。