cyclopent-3-en-1-ylmethyl methyl ether | 1370601-60-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: cyclopent-3-en-1-ylmethyl methyl ether
• 英文别名: 4-(methoxymethyl)cyclopent-1-ene；4-(Methoxymethyl)cyclopent-1-ene；4-(methoxymethyl)cyclopentene
• CAS: 1370601-60-7
• 化学式: C₇H₁₂O
• 分子量: 112.172
• InChiKey: NKXUKUPJOIOBRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  cyclopent-3-en-1-ylmethyl methyl ether 在 四氧化锇 、 水 、 N-甲基吗啉氧化物 作用下， 以 叔丁醇 为溶剂， 反应 48.0h， 生成 4-(methoxymethyl)cyclopentane-cis-1,2-diol 、 4-(methoxymethyl)cyclopentane-cis-1,2-diol
  参考文献：
  名称：

  Heterogeneous platinum catalytic aerobic oxidation of cyclopentane-1,2-diols to cyclopentane-1,2-diones

  摘要：

  A method for the aerobic oxidation of cyclopentane-1,2-diols to the corresponding diketones over a commercial heterogeneous Pt/C catalyst is described. Unsubstituted and 3- or 4-substituted cyclopentane-1,2-diols are oxidized to 1,2-dicarbonyl compounds in good yields under the reported optimized reaction conditions (atmospheric air, 1 mol % of catalyst, 1 equiv of LiOH, aqueous solvents and 60 degrees C temperature). The method is applicable for producing cyclopentane-1,2-diketones in a scalable manner. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.03.104
• 作为产物：
  描述：

  1-羟甲基-3-环戊烯 、 碘甲烷 在 sodium hydride 作用下， 以 四氢呋喃 、 mineral oil 为溶剂， 生成 cyclopent-3-en-1-ylmethyl methyl ether
  参考文献：
  名称：

  Heterogeneous platinum catalytic aerobic oxidation of cyclopentane-1,2-diols to cyclopentane-1,2-diones

  摘要：

  A method for the aerobic oxidation of cyclopentane-1,2-diols to the corresponding diketones over a commercial heterogeneous Pt/C catalyst is described. Unsubstituted and 3- or 4-substituted cyclopentane-1,2-diols are oxidized to 1,2-dicarbonyl compounds in good yields under the reported optimized reaction conditions (atmospheric air, 1 mol % of catalyst, 1 equiv of LiOH, aqueous solvents and 60 degrees C temperature). The method is applicable for producing cyclopentane-1,2-diketones in a scalable manner. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.03.104

文献信息

• Heterogeneous platinum catalytic aerobic oxidation of cyclopentane-1,2-diols to cyclopentane-1,2-diones
  作者：Indrek Reile、Sigrid Kalle、Franz Werner、Ivar Järving、Marina Kudrjashova、Anne Paju、Margus Lopp

  DOI：10.1016/j.tet.2014.03.104

  日期：2014.6

  A method for the aerobic oxidation of cyclopentane-1,2-diols to the corresponding diketones over a commercial heterogeneous Pt/C catalyst is described. Unsubstituted and 3- or 4-substituted cyclopentane-1,2-diols are oxidized to 1,2-dicarbonyl compounds in good yields under the reported optimized reaction conditions (atmospheric air, 1 mol % of catalyst, 1 equiv of LiOH, aqueous solvents and 60 degrees C temperature). The method is applicable for producing cyclopentane-1,2-diketones in a scalable manner. (C) 2014 Elsevier Ltd. All rights reserved.