N-methyl-O-[3-(perfluorooctyl)propyl]-N-(β-D-maltotetrapyranosyl)hydroxylamine | 1011478-36-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-methyl-O-[3-(perfluorooctyl)propyl]-N-(β-D-maltotetrapyranosyl)hydroxylamine
• CAS: 1011478-36-6
• 化学式: C₃₆H₅₀F₁₇NO₂₁
• 分子量: 1155.76
• InChiKey: KQMLWVJKMQTKLE-YJZCVGQKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.09
• 重原子数：
  75.0
• 可旋转键数：
  22.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  340.07
• 氢给体数：
  13.0
• 氢受体数：
  22.0

反应信息

• 作为产物：
  描述：

  N-methyl-3-(perfluorooctyl)propylhydroxylamine 、 maltotetraose 以 乙腈 为溶剂， 生成 N-methyl-O-[3-(perfluorooctyl)propyl]-N-(β-D-maltotetrapyranosyl)hydroxylamine
  参考文献：
  名称：

  Synthesis of Fluorous Tags for Incorporation of Reducing Sugars into a Quantitative Microarray Platform

  摘要：

  Carbohydrate microarrays can map out key interactions of carbohydrates and proteins in a high-throughput manner, but require the inclusion of a range of sugars for their optimal use. Here we present the synthesis and use of a new hydroxylamine-modified fluorous tag that allows the facile incorporation of reducing sugars into a noncovalent fluorous-based microarray after simple purification by fluorous solid-phase extraction (FSPE). The microarray supports quantitative screening against carbohydrate-binding proteins.

  DOI：

  10.1021/ol702915e