4-(5-Aminopentyl)-chinolin | 59082-54-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-(5-Aminopentyl)-chinolin
• 英文别名: 5-Quinolin-4-ylpentan-1-amine
• CAS: 59082-54-1
• 化学式: C₁₄H₁₈N₂
• 分子量: 214.31
• InChiKey: ZBFXQKXWSJBFRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  38.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• QUINAZOLINE DERIVATIVES AND THEIR USE AS DNA METHYLTRANSFERASE INHIBITORS
  申请人：Pierre Fabre Médicament

  公开号：EP3046917B1

  公开（公告）日：2017-11-08
• US9951044B2
  申请人：——

  公开号：US9951044B2

  公开（公告）日：2018-04-24
• [EN] COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, OR AMELIORATING INFLAMMATORY PAIN<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE TRAITEMENT, DE SUPPRESSION, DE RÉDUCTION OU D'AMÉLIORATION D'UNE DOULEUR INFLAMMATOIRE
  申请人：BAUSCH & LOMB

  公开号：WO2012170175A1

  公开（公告）日：2012-12-13

  A composition for treating, controlling, reducing, or ameliorating inflammatory pain comprises a dissociated glucocorticoid receptor agonist ("DIGRA"), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester thereof. The composition can comprise an additional anti-inflammatory agent and can be formulated for topical application, injection, or implantation. It may be used in a method of managing post-surgical ocular pain such that it has lower risk of eliciting adverse side effects seen with other therapeutic agents.