(S)-1-tert-butoxy-2-methyl-butane | 2203-46-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (S)-1-tert-butoxy-2-methyl-butane
• 英文别名: (S)-tert.-Butyl-(2-methyl-butyl)-aether；(2S)-2-methyl-1-[(2-methylpropan-2-yl)oxy]butane
• CAS: 2203-46-5
• 化学式: C₉H₂₀O
• 分子量: 144.257
• InChiKey: LTSQRKMUKSTWKM-QMMMGPOBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  S-(-)-2-甲基-1-丁醇 、 叔丁醇 在 硫酸 作用下， 生成 (S)-1-tert-butoxy-2-methyl-butane
  参考文献：
  名称：

  Salvadori,P.; Lardicci,L., Gazzetta Chimica Italiana, 1964, vol. 94, p. 1205 - 1220

  摘要：

  DOI：

文献信息

• BISPHENOL COMPOUNDS AND METHODS FOR THEIR USE
  申请人：Andersen Raymond John

  公开号：US20140248263A1

  公开（公告）日：2014-09-04

  Compounds having a structure of Formula I: wherein G, a, Q, L 2 , R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are as defined herein are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.

  提供具有公式I结构的化合物，其中G，a，Q，L2，R1，R2，R3，R4，R5和R6的定义如本文所述。提供了这种化合物用于治疗各种适应症，包括前列腺癌以及涉及这种化合物的治疗方法。
• BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS
  申请人：Sadar Marianne D.

  公开号：US20130131167A1

  公开（公告）日：2013-05-23

  This invention provides bisphenol derivatives having a structure of formula 1. Said compounds are modulators of the androgen receptor activity and are useful in the treatment of various diseases, including prostate cancer, breast cancer, ovarian cancer, endometrial cancer, acne, ovarian cysts, polycystic ovarian disease, age-related macular degeneration, precocious puberty, hirsutism and hair loss.
• BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE
  申请人：Sadar Marianne D.

  公开号：US20130109758A1

  公开（公告）日：2013-05-02

  This invention provides compounds having a structure of Formula (I). Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.
• US9388112B2
  申请人：——

  公开号：US9388112B2

  公开（公告）日：2016-07-12