N-allyl-N-((3S,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-methoxytetrahydrofuran-3-yl)acetamide | 1236041-15-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-allyl-N-((3S,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-methoxytetrahydrofuran-3-yl)acetamide
• CAS: 1236041-15-8
• 化学式: C₂₅H₃₁NO₅
• 分子量: 425.525
• InChiKey: AVBJKBIVAPYSHJ-XXRNLSRLSA-N

反应信息

• 作为反应物：
  描述：

  N-allyl-N-((3S,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-methoxytetrahydrofuran-3-yl)acetamide 在 trityl tetrafluoroborate 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以93%的产率得到N-allyl-N-((3S,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-hydroxytetrahydrofuran-3-yl)acetamide
  参考文献：
  名称：

  Synthesis of 1,4-dideoxy-1,4-iminoheptitol and 1,5-dideoxy-1,5-iminooctitols from d-xylose

  摘要：

  The synthesis of iminosugars from inexpensive D-xylose in high yields has been developed. The key step in this synthesis involves Wittig olefination or chelation-controlled attack of Grignard reagents on lactol and ring-closing metathesis using first or second generation Grubbs' catalysts. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.04.016
• 作为产物：
  描述：

  N-((3S,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-methoxytetrahydrofuran-3-yl)acetamide 、 3-溴丙烯 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 以92%的产率得到N-allyl-N-((3S,4R,5R)-4-(benzyloxy)-5-(benzyloxymethyl)-2-methoxytetrahydrofuran-3-yl)acetamide
  参考文献：
  名称：

  Synthesis of 1,4-dideoxy-1,4-iminoheptitol and 1,5-dideoxy-1,5-iminooctitols from d-xylose

  摘要：

  The synthesis of iminosugars from inexpensive D-xylose in high yields has been developed. The key step in this synthesis involves Wittig olefination or chelation-controlled attack of Grignard reagents on lactol and ring-closing metathesis using first or second generation Grubbs' catalysts. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2010.04.016