4,4,4-trifluoro-1-(9-pentyl-9H-carbazol-3-yl)butane-1,3-dione | 1193404-33-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 4,4,4-trifluoro-1-(9-pentyl-9H-carbazol-3-yl)butane-1,3-dione
• 英文别名: 4,4,4-trifluoro-1-(9-pentylcarbazole-3-yl)-1,3-butanedione
• CAS: 1193404-33-9
• 化学式: C₂₁H₂₀F₃NO₂
• 分子量: 375.391
• InChiKey: RWUGRARMLVLLPE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.69
• 重原子数：
  27.0
• 可旋转键数：
  7.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  39.07
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  1,10-菲罗啉 、 4,4,4-trifluoro-1-(9-pentyl-9H-carbazol-3-yl)butane-1,3-dione 、 氯化铕(III) 以 ethanol 为溶剂， 以81%的产率得到[Eu(THA)3(1,10-phenanthroline)]
  参考文献：
  名称：

  Effect of Different Alkyl Groups at the N-Position on the Luminescence of Carbazole-Based β-Diketonate Europium(III) Complexes

  摘要：

  A series of carbazole-based beta-diketone derivatives and their europium(III) ternary complexes Eu(N-Cx)(3)phen were designed and synthesized, where N-Cx denotes carbazole-based beta-diketonates with different alkyl substituents at N-position of the carbazole ring and phen is 1,10-phenethroline. Thermogravimetric analysis (TGA) shows that the decomposition temperature of the complexes is over 360 degrees C. UV-visible absorption spectroscopy, photoluminescence (PL), and the luminescence quantum yield of the Eu(III) complexes were measured and compared with each other, and the effect of different substituted-alkyls at N-position in the carbazole ring on the photoluminescence was discussed in details, indicating there exists a competition between the absorption capacity and the energy transfer efficiency for the complexes when the structure of the substituted-alkyls changes. The triplet state energy levels of the beta-diketonate ligands in the complexes are higher than that of the lowest excited level of Eu3+ ion, D-5(0), so the photoluminescence mechanism of the Eu(HI) complexes was proposed as a ligand-sensitized luminescence process. Red LEDs were fabricated by precoating the complexes onto 395 nm emitting InGaN chips. All the results show that this series of Eu(III) complexes is a promising candidate as a red component in fabrication of NUV-based white LEDs.

  DOI：

  10.1021/jp908416q
• 作为产物：
  描述：

  1-溴戊烷 在 aluminum (III) chloride 、 potassium tert-butylate 、 sodium hydroxide 作用下， 以 四氢呋喃 、 氯仿 、 丙酮 、 叔丁醇 为溶剂， 反应 98.33h， 生成 4,4,4-trifluoro-1-(9-pentyl-9H-carbazol-3-yl)butane-1,3-dione
  参考文献：
  名称：

  两光子敏化的空心Gd2O3：Eu3 +纳米复合材料用于实时双模成像和监测抗癌药物的释放

  摘要：

  新的双光子敏化多功能纳米复合材料设计用于通过光致发光（PL）和磁共振成像（MRI）进行双模成像和实时药物释放监测。通过基于协调的药物装载...

  DOI：

  10.1039/c5cc07609a

文献信息

• NIR light/H₂O₂-triggered nanocomposites for a highly efficient and selective synergistic photodynamic and photothermal therapy against hypoxic tumor cells
  作者：Yu Zhang、Ting-Ting Shen、Alexander M. Kirillov、Wei-Sheng Liu、Yu Tang

  DOI：10.1039/c6cc02571d

  日期：——

  Smart nanocomposites were designed and applied for an efficient synergistic photodynamic and photothermal therapy under single NIR laser excitation to overcome the hypoxia-induced drug resistance.

  智能纳米复合材料被设计并应用于单一近红外激光激发下的高效协同光动力疗法和光热疗法，以克服缺氧诱导的药物抗性。