1-chloro-1-(1,1,7-trihydroperfluoroheptoxy)ethane | 124734-40-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-chloro-1-(1,1,7-trihydroperfluoroheptoxy)ethane
• 英文别名: 7-(1-chloroethoxy)-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluoroheptane
• CAS: 124734-40-3
• 化学式: C₉H₇ClF₁₂O
• 分子量: 394.588
• InChiKey: ZBYYVOCNJPKXCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.03
• 重原子数：
  23.0
• 可旋转键数：
  8.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  甲醇 、 1-chloro-1-(1,1,7-trihydroperfluoroheptoxy)ethane 以91%的产率得到1-methoxy-1-(1',1',7'-trihydroperfluoroheptoxy)ethane
  参考文献：
  名称：

  Synthesis of α-chloropolyfluoroalkyl ethers and acetals based on them

  摘要：

  alpha-Chloropolyfluoroalkyl ethers were synthesized by the reaction of polyfluorinated alcohols H(CF(2)CF(2)) (n) CH(2)OH (n=1-3) with aliphatic aldehydes (ethanal, propanal, butanal) and hydrogen chloride. Yield of alpha-chloroethers decreases from 71 to 61% as the number of carbon atoms in the starting reactants increases. alpha-Chloropolyfluoroalkyl ethers react with polyfluorinated alcohols (n = 1-3) to form acetals in yield of up to 40-61%, and with methanol and ethanol, up to 98%.

  DOI：

  10.1134/s1070363211030194
• 作为产物：
  描述：

  十二氟庚醇 、 乙醛 在 盐酸 作用下， 以 氯仿 为溶剂， 反应 2.5h， 以66%的产率得到1-chloro-1-(1,1,7-trihydroperfluoroheptoxy)ethane
  参考文献：
  名称：

  Synthesis of α-chloropolyfluoroalkyl ethers and acetals based on them

  摘要：

  alpha-Chloropolyfluoroalkyl ethers were synthesized by the reaction of polyfluorinated alcohols H(CF(2)CF(2)) (n) CH(2)OH (n=1-3) with aliphatic aldehydes (ethanal, propanal, butanal) and hydrogen chloride. Yield of alpha-chloroethers decreases from 71 to 61% as the number of carbon atoms in the starting reactants increases. alpha-Chloropolyfluoroalkyl ethers react with polyfluorinated alcohols (n = 1-3) to form acetals in yield of up to 40-61%, and with methanol and ethanol, up to 98%.

  DOI：

  10.1134/s1070363211030194

文献信息

• KUTYGA, O. M.;PRONINA, I. I., SINTEZ HOB. POLITSIKLICH. I GETEROTSIKLICH. SOED., KUJBYSHEV,(1989) S. 98+
  作者：KUTYGA, O. M.、PRONINA, I. I.

  DOI：——

  日期：——