2-(2-acetylphenyl)-N,N-dimethylacetamide | 1607795-82-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(2-acetylphenyl)-N,N-dimethylacetamide
• CAS: 1607795-82-3
• 化学式: C₁₂H₁₅NO₂
• 分子量: 205.257
• InChiKey: OAZCIZJLPRFGJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.52
• 重原子数：
  15.0
• 可旋转键数：
  3.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  37.38
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2-(2-acetylphenyl)-N,N-dimethylacetamide 、 methoxymethyltriphenylphosphonium iodide 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 以66.667%的产率得到
  参考文献：
  名称：

  Synthesis of strigolactones analogues by intramolecular [2+2] cycloaddition of ketene-iminium salts to olefins and their activity on Orobanche cumana seeds

  摘要：

  Strigolactones have been the latest identified phytohormones. Among the strigolactones analogues described recently, GR-24 remains the most studied derivative which is used as standard in this field. In order to improve several properties of GR-24 for potential agronomical applications, we investigated the effect of substituents on the B and C-rings on the activity for seed germination induction. We report here the synthesis of 9 GR-24 analogues via a [2+2] intramolecular cycloaddition of ketene-iminium salts and a summary of their activity for the germination of Orobanche cumana (broomrape) seeds. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2014.03.044
• 作为产物：
  描述：

  2-(2-碘苯基)-N,N-二甲基乙酰胺 在 盐酸 、 四(三苯基膦)钯 作用下， 以 四氢呋喃 、 水 、 甲苯 为溶剂， 生成 2-(2-acetylphenyl)-N,N-dimethylacetamide
  参考文献：
  名称：

  Synthesis of strigolactones analogues by intramolecular [2+2] cycloaddition of ketene-iminium salts to olefins and their activity on Orobanche cumana seeds

  摘要：

  Strigolactones have been the latest identified phytohormones. Among the strigolactones analogues described recently, GR-24 remains the most studied derivative which is used as standard in this field. In order to improve several properties of GR-24 for potential agronomical applications, we investigated the effect of substituents on the B and C-rings on the activity for seed germination induction. We report here the synthesis of 9 GR-24 analogues via a [2+2] intramolecular cycloaddition of ketene-iminium salts and a summary of their activity for the germination of Orobanche cumana (broomrape) seeds. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2014.03.044