| 226069-61-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 226069-61-0
• 化学式: C₄₉H₆₈O₂₈
• 分子量: 1105.06
• InChiKey: XSNDWCJHSPOZPN-AHWYZFDNSA-N

反应信息

• 作为反应物：
  描述：

  在 ammonium cerium(IV) nitrate 作用下， 以 水 、 乙腈 为溶剂， 反应 1.0h， 以81%的产率得到[(2R,3R,4S,5R,6R)-5-acetyloxy-6-[(2R,3R,4S,5R,6S)-5-acetyloxy-6-[(2R,3R,4S,5R,6R)-5-acetyloxy-6-[[(1R,2R,3S,4R,5R)-4-acetyloxy-3-methoxy-6,8-dioxabicyclo[3.2.1]octan-2-yl]oxy]-2-(acetyloxymethyl)-4-methoxyoxan-3-yl]oxy-2-(acetyloxymethyl)-4-methoxyoxan-3-yl]oxy-3-hydroxy-4-methoxyoxan-2-yl]methyl acetate
  参考文献：
  名称：

  Synthetic oligosaccharides having various functional domains: Potent and potentially safe heparin mimetics

  摘要：

  A synthetic heptadecasaccharide, comprising an antithrombin III binding domain, a thrombin binding domain, and a neutral methylated hexasaccharide sequence, was obtained through a convergent synthesis. This compound displayed in vitro anticoagulant properties similar to that of standard heparin but, in contrast with heparin, escaped neutralization by platelet factor 4, a protein released by activated platelets. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00156-0
• 作为产物：
  描述：

  Acetic acid (2R,3R,4R,5R)-5-hydroxy-6-((1R,2R,3R,4R,5R)-4-hydroxy-3-methoxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-4-methoxy-3-(4-methoxy-phenoxy)-tetrahydro-pyran-2-ylmethyl ester 在 4-二甲氨基吡啶 、 ammonium cerium(IV) nitrate 、 4 A molecular sieve 、 叔丁基二甲硅基三氟甲磺酸酯 、 三乙胺 作用下， 以 二氯甲烷 、 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 5.83h， 生成
  参考文献：
  名称：

  Synthetic oligosaccharides having various functional domains: Potent and potentially safe heparin mimetics

  摘要：

  A synthetic heptadecasaccharide, comprising an antithrombin III binding domain, a thrombin binding domain, and a neutral methylated hexasaccharide sequence, was obtained through a convergent synthesis. This compound displayed in vitro anticoagulant properties similar to that of standard heparin but, in contrast with heparin, escaped neutralization by platelet factor 4, a protein released by activated platelets. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(99)00156-0