| 1373354-43-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• CAS: 1373354-43-8
• 化学式: C₁₈H₁₇ClN₂O₃
• 分子量: 344.798
• InChiKey: BSEXUFPJMLGHLF-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 4-(2-Tert-butylanilino)-7-(3,5-dimethyl-1,2-oxazol-4-yl)-6-methylquinoline-3-carboxylic acid
  参考文献：
  名称：

  From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151

  摘要：

  The discovery, synthesis and biological evaluation of a novel series of 7-isoxazoloquinolines is described. Several analogs are shown to increase ApoA1 expression within the nanomolar range in the human hepatic cell line HepG2. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.01.125
• 作为产物：
  描述：

  3,5-Dimethyl-4-(2-methyl-5-nitrophenyl)-1,2-oxazole 在 二苯醚 、 三氯氧磷 作用下， 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151

  摘要：

  The discovery, synthesis and biological evaluation of a novel series of 7-isoxazoloquinolines is described. Several analogs are shown to increase ApoA1 expression within the nanomolar range in the human hepatic cell line HepG2. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.01.125