3.5-di(2-hydroxyethyl)pyrazole | 1322736-98-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 3.5-di(2-hydroxyethyl)pyrazole
• 英文别名: 2-[3-(2-hydroxyethyl)-1H-pyrazol-5-yl]ethanol
• CAS: 1322736-98-0
• 化学式: C₇H₁₂N₂O₂
• 分子量: 156.184
• InChiKey: ULKNBVHMNBWEQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  69.1
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3.5-di(2-hydroxyethyl)pyrazole 在 氯化亚砜 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 以69%的产率得到3,5-di(chloroethyl)pyrazolium chloride
  参考文献：
  名称：

  3,5-Bis(diphenylphosphinoethyl)pyrazolate ligand (PNNPC2) and its dirhodium complexes: Comparison with related quadridentate dinucleating diphenylphosphinomethyl (PNNPPy) and phthalazine derivatives (PNNPPh)

  摘要：

  Dirhodium carbonyl complex with the 3,5-bis(diphenylphosphinoethyl) pyrazolato ligand (PNNPC2), [(mu-kappa(2): kappa(2)-PNNPC2) Rh-2(CO)(3)]BF4, is prepared and its reactivity is studied as compared with the previously reported 3,5-bis(diphenylphosphinomethyl)pyrazolate (PNNP), [(mu-kappa(2): kappa(2)-PNNP){Rh(CO)(2)}(2)]BF4, and 1,4-bis( diphenylphosphinomethyl) phthalazine (PNNPPh) derivatives, [(mu-kappa(2): kappa(2)-PNNPPh){Rh(CO)(2)}(2)](BF4)(2). The three quadridentate ligands are different in the size of the central ring and the charge; six-membered ring/neutral (PNNPC2) vs. five-membered ring/mono-negative (PNNP) vs. six-membered ring/neutral (PNNPPh). The number of the carbonyl ligands (n) in the dirhodium carbonyl complexes, [(mu-PNNP) Rh-2(CO)(n)](BF4)(x), is dependent on the dinucleating ligand: n = 2 (PNNPPh), 3 (PNNPC2) and 4 (PNNPPy). The three dirhodium carbonyl complexes serve as 4e-acceptors, and their reactivities turn out to be very similar as can be seen from formation of the analogous, unique tetranuclear l4-acetylide ([(mu-PNNP)(2){Rh(CO)}(4)(mu(4)-C C-R)](BF4)(x)) and mu(4)-dicarbide complexes ([(mu-PNNP)(2){Rh(CO)}(4)(mu(4)-C-2)](BF4)(x)). (C) 2011 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2011.02.040
• 作为产物：
  描述：

  dimethyl 2,2'-(1H-pyrazole-3,5-diyl)diacetate 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 10.0h， 以96%的产率得到3.5-di(2-hydroxyethyl)pyrazole
  参考文献：
  名称：

  3,5-Bis(diphenylphosphinoethyl)pyrazolate ligand (PNNPC2) and its dirhodium complexes: Comparison with related quadridentate dinucleating diphenylphosphinomethyl (PNNPPy) and phthalazine derivatives (PNNPPh)

  摘要：

  Dirhodium carbonyl complex with the 3,5-bis(diphenylphosphinoethyl) pyrazolato ligand (PNNPC2), [(mu-kappa(2): kappa(2)-PNNPC2) Rh-2(CO)(3)]BF4, is prepared and its reactivity is studied as compared with the previously reported 3,5-bis(diphenylphosphinomethyl)pyrazolate (PNNP), [(mu-kappa(2): kappa(2)-PNNP){Rh(CO)(2)}(2)]BF4, and 1,4-bis( diphenylphosphinomethyl) phthalazine (PNNPPh) derivatives, [(mu-kappa(2): kappa(2)-PNNPPh){Rh(CO)(2)}(2)](BF4)(2). The three quadridentate ligands are different in the size of the central ring and the charge; six-membered ring/neutral (PNNPC2) vs. five-membered ring/mono-negative (PNNP) vs. six-membered ring/neutral (PNNPPh). The number of the carbonyl ligands (n) in the dirhodium carbonyl complexes, [(mu-PNNP) Rh-2(CO)(n)](BF4)(x), is dependent on the dinucleating ligand: n = 2 (PNNPPh), 3 (PNNPC2) and 4 (PNNPPy). The three dirhodium carbonyl complexes serve as 4e-acceptors, and their reactivities turn out to be very similar as can be seen from formation of the analogous, unique tetranuclear l4-acetylide ([(mu-PNNP)(2){Rh(CO)}(4)(mu(4)-C C-R)](BF4)(x)) and mu(4)-dicarbide complexes ([(mu-PNNP)(2){Rh(CO)}(4)(mu(4)-C-2)](BF4)(x)). (C) 2011 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2011.02.040

文献信息

• Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer
  申请人：NAKAHARA Shinya

  公开号：US20080227937A1

  公开（公告）日：2008-09-18

  A process for producing an olefin copolymerization catalyst, comprising the step of contacting, with one another, (A) a solid catalyst component containing a titanium atom, a magnesium atom and a halogen atom, (B) an organoaluminum compound and/or organoaluminumoxy compound, and (C) a nitrogen-containing aromatic heterocyclic compound, whose one or more carbon atoms adjacent to its nitrogen atom are linked to an electron-donating group, or a group containing an electron-donating group; and a process for producing an olefin copolymer using the an olefin copolymerization catalyst.
• US7605215B2
  申请人：——

  公开号：US7605215B2

  公开（公告）日：2009-10-20