Methyl-9-fluor-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzochinolizin-2-carboxylat | 42835-51-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: Methyl-9-fluor-6,7-dihydro-5-methyl-1-oxo-1H,5H-benzochinolizin-2-carboxylat
• 英文别名: 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid methyl ester；Methyl 7-fluoro-12-methyl-4-oxo-1-azatricyclo[7.3.1.05,13]trideca-2,5,7,9(13)-tetraene-3-carboxylate
• CAS: 42835-51-8
• 化学式: C₁₅H₁₄FNO₃
• 分子量: 275.279
• InChiKey: OFWHOYXPLWWGSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• A PROCESS FOR THE SYNTHESIS OF CARBON LABELED ORGANIC COMPOUNDS
  申请人：Commissariat à l'Energie Atomique et aux Energies Alternatives

  公开号：EP3549927A1

  公开（公告）日：2019-10-09

  The present invention relates to a process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group. The present invention also concerns the use of carbon labeled organic compounds containing a carbon labeled carboxyl group obtained by the process of the invention, in the manufacture of pharmaceuticals and agrochemicals, in particular pharmaceuticals and agrochemicals having a free carboxylic acid functionality. Another aspect of the invention relates to a process for manufacturing labeled pharmaceuticals and agrochemicals, in particular pharmaceuticals and agrochemicals having a free carboxylic acid functionality, comprising a step of synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl obtained by the process of the invention A still another aspect of the invention further relates to a process for producing tracers and radiotracers, characterized in that it comprises a step of synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group obtained by the process of the invention.

  本发明涉及一种合成含有碳标记羧基的碳标记有机化合物的工艺。 本发明还涉及将通过本发明工艺获得的含有碳标记羧基的碳标记有机化合物用于制造药物和农用化学品，特别是具有游离羧酸官能团的药物和农用化学品。 本发明的另一方面涉及一种制造标记药物和农用化学品，特别是具有游离羧酸官能团的药物和农用化学品的工艺，包括合成含有本发明工艺获得的碳标记羧基的碳标记有机化合物的步骤。 本发明的另一个方面还涉及一种生产示踪剂和放射性示踪剂的工艺，其特征在于该工艺包括合成通过本发明工艺获得的含有碳标记羧基的碳标记有机化合物的步骤。
• US3995052A
  申请人：——

  公开号：US3995052A

  公开（公告）日：1976-11-30
• US4001243A
  申请人：——

  公开号：US4001243A

  公开（公告）日：1977-01-04
• US3969463A
  申请人：——

  公开号：US3969463A

  公开（公告）日：1976-07-13
• US3985882A
  申请人：——

  公开号：US3985882A

  公开（公告）日：1976-10-12