| 287945-02-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 287945-02-2
• 化学式: C₄₂H₄₂O₁₀S
• 分子量: 738.855
• InChiKey: GRNNMLYWZFQJFU-DKNYHCEJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  53.0
• 可旋转键数：
  8.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  92.3
• 氢给体数：
  0.0
• 氢受体数：
  11.0

反应信息

• 作为反应物：
  描述：

  在 4-甲基苯磺酸吡啶 作用下， 以 甲醇 、 氯仿 为溶剂， 以79%的产率得到
  参考文献：
  名称：

  Total synthesis of calonyctin A2, a macrolidic glycolipid with plant growth-promoting activity

  摘要：

  Calonyctin A2, a tetrasaccharidic glycolipid having a 22-membered macrolidic structure, has been synthesized by the assembly of three 6-deoxygenated thioglycoside intermediates. The short-step synthesis was achieved by preparation of the most complicated b-c disaccharide unit from phenyl 2,2':4,6:4',6'-tri-O-benzylidene-1-thio-beta-D-laminaribioside without any glycosidation reaction and by regioselective macrolactonization. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00427-5
• 作为产物：
  描述：

  3-溴丙烯 、 (1S,3S,4R,6R,9R,11S,12R,16R,17S,18S,20R,23R)-6,14,20-triphenyl-11-phenylsulfanyl-2,5,7,10,13,15,19,21,24-nonaoxapentacyclo[14.8.0.03,12.04,9.018,23]tetracosan-17-ol 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  Total synthesis of calonyctin A2, a macrolidic glycolipid with plant growth-promoting activity

  摘要：

  Calonyctin A2, a tetrasaccharidic glycolipid having a 22-membered macrolidic structure, has been synthesized by the assembly of three 6-deoxygenated thioglycoside intermediates. The short-step synthesis was achieved by preparation of the most complicated b-c disaccharide unit from phenyl 2,2':4,6:4',6'-tri-O-benzylidene-1-thio-beta-D-laminaribioside without any glycosidation reaction and by regioselective macrolactonization. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00427-5