3,4-Isopropyliden-cyclohexen-3,4-diol | 220424-59-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-Isopropyliden-cyclohexen-3,4-diol
• 英文别名: (3aS,7aR)-2,2-dimethyl-3a,4,5,7a-tetrahydro-1,3-benzodioxole
• CAS: 220424-59-9
• 化学式: C₉H₁₄O₂
• 分子量: 154.209
• InChiKey: GSYGCNYMFCTHEE-SFYZADRCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (S)-pent-4-en-2-yl 2,4-dihydroxy-6-((E)-4-((4S,5R)-2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)but-1-enyl)benzoate 在 Hoveyda-Grubbs catalyst second generation 作用下， 以 二氯甲烷 为溶剂， 以50%的产率得到Aigialomycin D acetonide
  参考文献：
  名称：

  Total Synthesis of Aigialomycin D using a One-Pot Ketene Generation−Trapping−Aromatization Sequence

  摘要：

  The total synthesis of aigialomycin D, without the need for phenol protection, was carried out using the C-acylation of a keto-dioxinone dianion, a cascade sequence consisting of ketene generation, alcohol trapping and aromatization, and ring-closing metathesis.

  DOI：

  10.1021/ol901979x

文献信息

• Synthesis of acetonides from aryl silanes
  申请人：McAuliffe C. Joseph

  公开号：US20070213541A1

  公开（公告）日：2007-09-13

  The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for converting silane cis-diols to the corresponding catechols and the compounds produced thereby. The present invention also provides chemical methods for the conversion of said silane cis-diols and acetonide compounds to epoxy, saturated and otherwise modified derivatives. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).
• Synthesis of cis-diols from aryl silanes
  申请人：Mcauliffe C. Joseph

  公开号：US20070213550A1

  公开（公告）日：2007-09-13

  The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for converting silane cis-diols to the corresponding catechols and the compounds produced thereby. The present invention also provides chemical methods for the conversion of said silane cis-diols and acetonide compounds to epoxy, saturated and otherwise modified derivatives. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims.
• US7179932B2
  申请人：——

  公开号：US7179932B2

  公开（公告）日：2007-02-20
• US7381830B2
  申请人：——

  公开号：US7381830B2

  公开（公告）日：2008-06-03
• US7456298B2
  申请人：——

  公开号：US7456298B2

  公开（公告）日：2008-11-25